YRC Public Data Repository - Protein Structure Prediction

Protein:	RPSA
Organism:	Homo sapiens
Length:	295 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPSA.

Description	E-value	Query Range	Subject Range
gi\|61370578, gi\|... - gi\|61370584\|gb\|AAX43520.1\| laminin receptor 1 [synthetic construct], gi\|61370578\|gb\|AAX43519.1\| lami...	0.0	[1..295]	[1..295]
gi\|30047125 - gi\|30047125\|gb\|AAH50688.1\| Ribosomal protein SA [Homo sapiens]	0.0	[1..295]	[1..295]
RSSA_CHLAE - 40S ribosomal protein SA OS=Chlorocebus aethiops GN=RPSA PE=2 SV=3 gi\|90075168 - gi\|90075168\|dbj\|BAE87264.1\| unnamed protein product [Macaca fascicularis] ENSCJAT00000009364 - null gi\|109041469, gi... - gi\|109041484\|ref\|XP_001083829.1\| PREDICTED: similar to 40S ribosomal protein SA (p40) (34/67 kDa lam...	0.0	[1..295]	[1..295]
RSSA_RAT - 40S ribosomal protein SA OS=Rattus norvegicus GN=Rpsa PE=1 SV=3	0.0	[1..295]	[1..295]
gi\|114579031 - gi\|114579031\|ref\|XP_001154496.1\| PREDICTED: similar to 40S ribosomal protein SA (p40) (34/67 kDa lam...	0.0	[1..295]	[1..295]
gi\|78157165, gi\|... - gi\|78157165\|gb\|ABB22830.1\| laminin receptor 1 [Equus caballus], gi\|221139852\|ref\|NP_001137423.1\| lam... tr\|M3VZ17\|M3VZ17... - 40S ribosomal protein SA OS=Felis catus GN=RPSA PE=3 SV=1 gi\|73989780, gi\|... - gi\|73989797\|ref\|XP_860784.1\| PREDICTED: similar to 40S ribosomal protein SA (p40) (34/67 kDa laminin... gi\|126341360 - gi\|126341360\|ref\|XP_001368957.1\| PREDICTED: similar to laminin receptor [Monodelphis domestica]	0.0	[1..295]	[1..295]
RSSA_MOUSE - 40S ribosomal protein SA OS=Mus musculus GN=Rpsa PE=1 SV=4 gi\|148237408, gi... - gb\|AAH84019.1\| Unknown (protein for MGC:98191) [Xenopus laevis], gi\|148237408\|ref\|NP_001091273.1\| h... gi\|228997 - gi\|228997\|prf\|\|1815216A laminin receptor	0.0	[1..295]	[1..295]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL  60
   61 AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR 120
  121 LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR 180
  181 EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.39794
Match:	1s1hB
Description:	Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. This file, 1S1H, Contains 40S subunit. The 60S Ribosomal Subunit Is In File 1S1I.
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [218-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEKAVTKEEF QGEWTAPAPE FTATQPEVAD WSEGVQVPSV PIQQFPTEDW SAQPATEDWS  60
   61 AAPTAQATEW VGATTDWS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.306	0.092	structural constituent of ribosome	a.156.1	S13-like H2TH domain
View	Download	0.321	N/A	N/A	c.84.1	Phosphoglucomutase, first 3 domains
View	Download	0.378	N/A	N/A	d.52.1	Alpha-lytic protease prodomain
View	Download	0.319	N/A	N/A	a.118.11	Cytochrome c oxidase subunit E
View	Download	0.451	N/A	N/A	c.55.7	Methylated DNA-protein cysteine methyltransferase domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits