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View Structure Prediction Details

Protein: CNOT3
Organism: Homo sapiens
Length: 753 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CNOT3.

Description E-value Query
Range
Subject
Range
gi|40788331 - gi|40788331|dbj|BAA31666.2| KIAA0691 protein [Homo sapiens]
2.0E-85 [1..753] [10..762]
CNOT3_MOUSE - CCR4-NOT transcription complex subunit 3 OS=Mus musculus GN=Cnot3 PE=1 SV=1
3.0E-82 [1..753] [1..751]
gi|34854462 - gi|34854462|ref|XP_218187.2| PREDICTED: similar to CCR4-NOT transcription complex, subunit 3 [Rattus...
4.0E-82 [1..753] [1..751]
gi|73946887 - gi|73946887|ref|XP_541428.2| PREDICTED: similar to CCR4-NOT transcription complex subunit 3 (CCR4-as...
1.0E-78 [1..753] [1..752]
gi|76642580 - gi|76642580|ref|XP_605695.2| PREDICTED: similar to CCR4-NOT transcription complex subunit 3 (CCR4-as...
8.0E-77 [1..753] [1..744]
gi|50418265, gi|... - gi|50418265|gb|AAH77869.1| MGC80612 protein [Xenopus laevis], gi|148227574|ref|NP_001086992.1| MGC80...
7.0E-64 [1..753] [1..728]
gi|46102019, gi|... - gi|71024625|ref|XP_762542.1| hypothetical protein UM06395.1 [Ustilago maydis 521], ref|XP_404010.1| ...
4.0E-61 [5..749] [4..734]
gi|66550449 - gi|66550449|ref|XP_395261.2| PREDICTED: similar to lethal (2) NC136 CG8426-PA [Apis mellifera]
8.0E-61 [1..752] [1..683]

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Predicted Domain #1
Region A:
Residues: [1-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADKRKLQGE IDRCLKKVSE GVEQFEDIWQ KLHNAANANQ KEKYEADLKK EIKKLQRLRD  60
   61 QIKTWVASNE IKDKRQLIDN RKLIETQMER FKVVERETKT KAYSKEGLGL AQKVDPAQKE 120
  121 KEEVGQWLTN TIDTLNMQVD QFESEVESLS VQTRKKKGDK DKQDRIEGLK RHIEKHRYHV 180
  181 RMLETILRML DNDSILVDAI RKIKDDVEYY VDSSQDPDFE ENEFLYDDLD LEDIPQALVA 240
  241 TSPPSHSHME DEIFNQSSST PTST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1c1gA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [265-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSSPIPPSP ANCTTENSED DKKRGRSTDS EVSQSPAKNG SKPVHSNQHP QSPAVPPTYP  60
   61 SGPPPAASAL STTPGNNGVP APAAPPSALG PKASPAPSHN SGTPAPYAQA VAPPAPSGPS 120
  121 TTQPRPPSVQ PSGGGGGGSG GGGSSSSSNS SAGGGAGKQN GATSYSSVVA DSPAEVALSS 180
  181 SGGNNA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [451-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSQALGPPSG PHNPPPSTSK EPSAAAPTGA GGVAPGSGNN SGGPSLLVPL PVNPPSSPTP  60
   61 SFSDAKAAGA LLNGPPQFST APEIKAPEPL SSLKSMAERA AISSGIEDPV PTLHLTERDI 120
  121 ILSSTSAPPA SAQPPLQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [588-753]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSEVNIPLSL GVCPLGPVPL TKEQLYQQAM EEAAWHHMPH PSDSERIRQY LPRNPCPTPP  60
   61 YHHQMPPPHS DTVEFYQRLS TETLFFIFYY LEGTKAQYLA AKALKKQSWR FHTKYMMWFQ 120
  121 RHEEPKTITD EFEQGTYIYF DYEKWGQRKK EGFTFEYRYL EDRDLQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 35.79588
Match: PF04153.9
Description: No description for PF04153.9 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle