YRC Public Data Repository - Protein Structure Prediction

Protein:	GRPEL1
Organism:	Homo sapiens
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRPEL1.

Description	E-value	Query Range	Subject Range
gi\|74137770 - gi\|74137770\|dbj\|BAE24062.1\| unnamed protein product [Mus musculus]	2.0E-65	[1..217]	[1..217]
GRPE1_RAT - GrpE protein homolog 1, mitochondrial OS=Rattus norvegicus GN=Grpel1 PE=1 SV=2	2.0E-64	[1..217]	[1..217]
gi\|90085180 - gi\|90085180\|dbj\|BAE91331.1\| unnamed protein product [Macaca fascicularis] gi\|109073648 - gi\|109073648\|ref\|XP_001091412.1\| PREDICTED: GrpE-like 1, mitochondrial (E. coli) [Macaca mulatta]	1.0E-62	[1..217]	[1..217]
gi\|55726032 - gi\|55726032\|emb\|CAH89792.1\| hypothetical protein [Pongo abelii] gi\|197098918 - gi\|197098918\|ref\|NP_001127196.1\| GrpE-like 1, mitochondrial [Pongo abelii]	1.0E-62	[1..217]	[1..217]
GRPE1_BOVIN - GrpE protein homolog 1, mitochondrial OS=Bos taurus GN=GRPEL1 PE=1 SV=1	2.0E-62	[1..215]	[1..215]
gi\|11139093 - gi\|11139093\|gb\|AAG31605.1\|AF298592_1 GrpE-like protein cochaperone [Homo sapiens]	5.0E-62	[2..217]	[1..216]
gi\|73951739 - gi\|73951739\|ref\|XP_545902.2\| PREDICTED: similar to GrpE protein homolog 1, mitochondrial precursor (...	3.0E-56	[20..217]	[98..294]
gi\|57530061, gi\|... - gi\|57530061\|ref\|NP_001006458.1\| GrpE-like 1, mitochondrial [Gallus gallus], gi\|53136716\|emb\|CAG32687...	2.0E-53	[3..217]	[5..222]
gi\|82658254, gi\|... - gi\|82658254\|ref\|NP_001032461.1\| GrpE-like 1, mitochondrial [Danio rerio], gi\|81294299\|gb\|AAI08003.1\|...	7.0E-52	[1..215]	[1..215]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQCVRLAR RSLPALALSL RPSPRLLCTA TKQKNSGQNL EEDMGQSEQK ADPPATEKTL  60
   61 LEEKVKLEEQ LKETVEKYKR ALADTENLRQ RSQKLVEEAK LYGIQAFCKD LLEVADVLEK 120
  121 ATQCVPKEEI KDDNPHLKNL YEGLVMTEVQ IQKVFTKHGL LKLNPVGAKF DPYEHEALFH 180
  181 TPVEGKEPGT VALVSKVGYK LHGRTLRPAL VGVVKEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.30103
Match:	1dkgA
Description:	Head domain of nucleotide exchange factor GrpE; Coiled-coil domain of nucleotide exchange factor GrpE
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits