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View Structure Prediction Details

Protein: MPZL3
Organism: Homo sapiens
Length: 235 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPZL3.

Description E-value Query
Range
Subject
Range
gi|17066524 - gi|17066524|gb|AAL35301.1|AF354264_1 immunoglobulin gamma heavy chain A [Canis familiaris]
2.0E-49 [16..230] [5..216]
gi|60688323 - gi|60688323|gb|AAH91272.1| LOC367586 protein [Rattus norvegicus]
2.0E-49 [14..229] [3..213]
gi|49258106 - gi|49258106|gb|AAH73773.1| Immunoglobulin heavy variable 4-31 [Homo sapiens]
5.0E-49 [10..214] [1..209]
gi|12841781 - gi|12841781|dbj|BAB25349.1| unnamed protein product [Mus musculus]
6.0E-49 [14..229] [3..215]

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Predicted Domain #1
Region A:
Residues: [1-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQRGAAGSR GCALFPLLGV LFFQGVYIVF SLEIRADAHV RGYVGEKIKL KCTFKSTSDV  60
   61 TDKLTIDWTY RPPSSSHTVS IFHYQSFQYP TTAGTFRDRI SWVGNVYKGD ASISISNPTI 120
  121 KDNGTFSCAV KNPPDVHHNI PMTELTVTER GFGTMLSSVA LLSILVFVPS AVVVALLLVR 180
  181 MGRKAAGLKK RSRSGYKKSS IEVSDDTDQE EEEACMARLC VRCAECLDSD YEETY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.69897
Match: 1nl0L
Description: Crystal structure of human factor IX Gla domain in complex of an inhibitory antibody, 10C12
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.68891223191024 bayes_pls_golite062009
protein binding 0.667010091042187 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle