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View Structure Prediction Details

Protein: gi|113421490
Organism: Homo sapiens
Length: 663 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|113421490.

Description E-value Query
Range
Subject
Range
AGAP4 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
0.0 [1..663] [1..663]

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Predicted Domain #1
Region A:
Residues: [1-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNILTCRVH PSVSLEFDQQ QGSVCPSESE IYEAGAEDRM AGAPMAAAVQ PAEVTVEVGE  60
   61 DLHMHQVRDR EMPEALEFNP SANPEASTIF QRNSQTDVVE IRRSNCTNHV STVRFSQQYS 120
  121 LCSTIFLDDS TAIQHYLTMT IISVTLEIPH HITQRDADRS LSIPDEQLHS FAVSTVHIMK 180
  181 KRNGGGSLNN YSSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [195-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPPTPSTSQE DPQFSVPPTA NTPTPVCKRS MRWSNLFTSE KGSDPDKERK APENHADTIG  60
   61 SGRAIPIKQG MLLKRSGKWL KTWKKKYVTL CSNGVLTYYS SLGDYMKNIH KKEIDLQTST 120
  121 IKVPGKWPSL ATSACAPISS SKSNGLSKDM DIGLGDSICF SPSISSTTSP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 1u5eA
Description: Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [365-663]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLNPPPSPHA NKKKHLKKKS TNNFMIVSAT GQTWHFEATT YEERDAWVQA IQSQILASLQ  60
   61 SCESSKSKSQ LTSQSEAMAL QSIQNMRGNA HCVDCETQNP KWASLNLGVL MCIECSGIHR 120
  121 SLGTRLSRVR SLELDDWPVE LRKVMSSIGN DLANSIWEGS SQGQTKPSEK STREEKERWI 180
  181 RSKYEEKLFL APLPCTELSL GQQLLRATAD EDLQTAILLL AHGSREEVNE TCGEGDGCTA 240
  241 LHLACRKGNV VLAQLLIWYG VDVMARDAHG NTALTYARQA SSQECINVLL QYGCPDECV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.0
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle