YRC Public Data Repository - Protein Structure Prediction

Protein:	NFE2L1
Organism:	Homo sapiens
Length:	772 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NFE2L1.

Description	E-value	Query Range	Subject Range
gi\|21748606 - gi\|21748606\|dbj\|BAC03440.1\| FLJ00380 protein [Homo sapiens]	2.0E-99	[1..772]	[20..791]
gi\|109114143, gi... - gi\|109114143\|ref\|XP_001087204.1\| PREDICTED: nuclear factor (erythroid-derived 2)-like 1 isoform 13 [...	4.0E-99	[1..772]	[1..772]
gi\|55729299 - gi\|55729299\|emb\|CAH91385.1\| hypothetical protein [Pongo abelii] NF2L1_PONAB - Nuclear factor erythroid 2-related factor 1 OS=Pongo abelii GN=NFE2L1 PE=2 SV=1	2.0E-98	[1..772]	[1..772]
gi\|73966220, gi\|... - gi\|73966220\|ref\|XP_537663.2\| PREDICTED: similar to Nuclear factor erythroid 2 related factor 1 (NF-E...	2.0E-94	[1..772]	[1..781]
gi\|542952, gi\|14... - pir\|\|A49672 transcription factor Nrf1 - human, gi\|14714932\|gb\|AAH10623.1\| NFE2L1 protein [Homo sapie... gi\|123995137, gi... - gi\|123995137\|gb\|ABM85170.1\| nuclear factor (erythroid-derived 2)-like 1 [synthetic construct], gi\|12... gi\|114666378, gi... - gi\|114666378\|ref\|XP_001173218.1\| PREDICTED: nuclear factor (erythroid-derived 2)-like 1 isoform 6 [P...	1.0E-91	[1..772]	[1..742]
NF2L1_CHICK - Nuclear factor erythroid 2-related factor 1 OS=Gallus gallus GN=NFE2L1 PE=2 SV=1	9.0E-90	[1..772]	[1..772]
gi\|47847522 - gi\|47847522\|dbj\|BAD21433.1\| mFLJ00380 protein [Mus musculus]	4.0E-88	[1..772]	[27..767]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSLKKYLTE GLLQFTILLS LIGVRVDVDT YLTSQLPPLR EIILGPSSAY TQTQFHNLRN  60
   61 TLDGYGIHPK SIDLDNYFTA RRLLSQVRAL DRFQVPTTEV NAWLVHRDPE GSVSGSQPNS 120
  121 GLALESSSGL QDVTGPDNGV RESETEQGFG EDLEDLGAVA PPVSGDLTKE DIDLIDILWR 180
  181 QDIDLGAGRE VFDYSHRQKE QDVEKELRDG GEQDTW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [217-339]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGEGAEALAR NLLVDGETGE SFPAQVPSGE DQTALSLEEC LRLLEATCPF GENAEFPADI  60
   61 SSITEAVPSE SEPPALQNNL LSPLLTGTES PFDLEQQWQD LMSIMEMQAM EVNTSASEIL 120
  121 YSA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [340-465]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGDPLSTNY SLAPNTPINQ NVSLHQASLG GCSQDFLLFS PEVESLPVAS SSTLLPLAPS  60
   61 NSTSLNSTFG STNLTGLFFP PQLNGTANDT AGPELPDPLG GLLDEAMLDE ISLMDLAIEE 120
  121 GFNPVQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [466-617]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASQLEEEFDS DSGLSLDSSH SPSSLSSSEG SSSSSSSSSS SSSSASSSAS SSFSEEGAVG  60
   61 YSSDSETLDL EEAEGAVGYQ PEYSKFCRMS YQDPAQLSCL PYLEHVGHNH TYNMAPSALD 120
  121 SADLPPPSAL KKGSKEKQAD FLDKQMSRDE HR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [618-772]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARAMKIPFTN DKIINLPVEE FNELLSKYQL SEAQLSLIRD IRRRGKNKMA AQNCRKRKLD  60
   61 TILNLERDVE DLQRDKARLL REKVEFLRSL RQMKQKVQSL YQEVFGRLRD ENGRPYSPSQ 120
  121 YALQYAGDGS VLLIPRTMAD QQARRQERKP KDRRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.522879
Match:	2i1jA
Description:	No description for 2i1jA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits