YRC Public Data Repository - Protein Structure Prediction

Protein:	TIMM44
Organism:	Homo sapiens
Length:	452 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIMM44.

Description	E-value	Query Range	Subject Range
gi\|62897685 - gi\|62897685\|dbj\|BAD96782.1\| translocase of inner mitochondrial membrane 44 homolog [Homo sapiens]	0.0	[1..452]	[1..452]
gi\|114675079 - gi\|114675079\|ref\|XP_512338.2\| PREDICTED: translocase of inner mitochondrial membrane 44 [Pan troglod...	0.0	[16..452]	[263..699]
TIM44_MOUSE - Mitochondrial import inner membrane translocase subunit TIM44 OS=Mus musculus GN=Timm44 PE=1 SV=2	0.0	[1..452]	[1..452]
TIM44_RAT - Mitochondrial import inner membrane translocase subunit TIM44 OS=Rattus norvegicus GN=Timm44 PE=1 SV...	0.0	[1..452]	[1..453]
gi\|73987180 - gi\|73987180\|ref\|XP_542123.2\| PREDICTED: similar to Import inner membrane translocase subunit TIM44, ...	0.0	[1..452]	[1..454]
gi\|109123220 - gi\|109123220\|ref\|XP_001098363.1\| PREDICTED: translocase of inner mitochondrial membrane 44 homolog [...	0.0	[16..452]	[6..442]

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Predicted Domain #1

Region A:
Residues: [1-250]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAALRSGW CRCPRRCLGS GIQFLSSHNL PHGSTYQMRR PGGELPLSKS YSSGNRKGFL  60
   61 SGLLDNVKQE LAKNKEMKES IKKFRDEARR LEESDVLQEA RRKYKTIESE TVRTSEVLRK 120
  121 KLGELTGTVK ESLHEVSKSD LGRKIKEGVE EAAKTAKQSA ESVSKGGEKL GRTAAFRALS 180
  181 QGVESVKKEI DDSVLGQTGP YRRPQRLRKR TEFAGDKFKE EKVFEPNEEA LGVVLHKDSK 240
  241 WYQQWKDFKE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [251-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNVVFNRFFE MKMKYDESDN AFIRASRALT DKVTDLLGGL FSKTEMSEVL TEILRVDPAF  60
   61 DKDRFLKQCE NDIIPNVLEA MISGELDILK DWCYEATYSQ LAHPIQQAKA LGLQFHSRIL 120
  121 DIDNVDLAMG KMMEQGPVLI ITFQAQLVMV VRNPKGEVVE GDPDKVLRML YVWALCRDQD 180
  181 ELNPYAAWRL LDISASSTEQ IL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.522879
Match:	2cw9A
Description:	Crystal structure of human Tim44 C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits