YRC Public Data Repository - Protein Structure Prediction

Protein:	NOC4L
Organism:	Homo sapiens
Length:	516 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOC4L.

Description	E-value	Query Range	Subject Range
NOC4L_RAT - Nucleolar complex protein 4 homolog OS=Rattus norvegicus GN=Noc4l PE=2 SV=1	0.0	[1..516]	[1..516]
NOC4L_MOUSE - Nucleolar complex protein 4 homolog OS=Mus musculus GN=Noc4l PE=2 SV=1	0.0	[1..516]	[1..516]
gi\|109099286 - gi\|109099286\|ref\|XP_001105967.1\| PREDICTED: similar to nucleolar complex associated 4 homolog [Macac...	0.0	[1..516]	[1..516]
gi\|39644583 - gi\|39644583\|gb\|AAH07893.2\| NOC4L protein [Homo sapiens]	0.0	[23..516]	[1..494]
gi\|57105758 - gi\|57105758\|ref\|XP_543350.1\| PREDICTED: similar to nucleolar complex associated 4 homolog [Canis fam...	0.0	[1..516]	[1..516]
NOC4B_XENLA - Nucleolar complex protein 4 homolog B OS=Xenopus laevis GN=noc4l-b PE=2 SV=1	0.0	[6..515]	[16..525]

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Predicted Domain #1

Region A:
Residues: [1-516]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEREPGAAGV RRALGRRLEA VLASRSEANA VFDILAVLQS EDQEEIQEAV RTCSRLFGAL  60
   61 LERGELFVGQ LPSEEMVMTG SQGATRKYKV WMRHRYHSCC NRLGELLGHP SFQVKELALS 120
  121 ALLKFVQLEG AHPLEKSKWE GNYLFPRELF KLVVGGLLSP EEDQSLLLSQ FREYLDYDDT 180
  181 RYHTMQAAVD AVARVTGQHP EVPPAFWNNA FTLLSAVSLP RREPTVSSFY VKRAELWDTW 240
  241 KVAHLKEHRR VFQAMWLSFL KHKLPLSLYK KVLLIVHDAI LPQLAQPTLM IDFLTRACDL 300
  301 GGALSLLALN GLFILIHKHN LEYPDFYRKL YGLLDPSVFH VKYRARFFHL ADLFLSSSHL 360
  361 PAYLVAAFAK RLARLALTAP PEALLMVLPF ICNLLRRHPA CRVLVHRPHG PELDADPYDP 420
  421 GEEDPAQSRA LESSLWELQA LQRHYHPEVS KAASVINQAL SMPEVSIAPL LELTAYEIFE 480
  481 RDLKKKGPEP VPLEFIPAQG LLGRPGELCA QHFTLS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.12
Match:	1gw5B
Description:	Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.94245645040501	bayes_pls_golite062009
protein binding	0.40342012399316	bayes_pls_golite062009
RNA binding	0.355270528730177	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: