YRC Public Data Repository - Protein Structure Prediction

Protein:	ABHD14B
Organism:	Homo sapiens
Length:	210 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ABHD14B.

Description	E-value	Query Range	Subject Range
gi\|50919593, gi\|... - gi\|50919593\|ref\|XP_470157.1\| putative hydrolase [Oryza sativa], gi\|28372678\|gb\|AAO39862.1\| putative ...	1.0E-29	[1..155]	[1..152]
ABHEB_PONPY, AB1... - Abhydrolase domain-containing protein 14B - Pongo pygmaeus (Orangutan), Abhydrolase domain-containin... ABHEB_PONAB - Protein ABHD14B OS=Pongo abelii GN=ABHD14B PE=2 SV=1	3.0E-29	[1..210]	[1..210]
gi\|30047108 - gi\|30047108\|gb\|AAH50650.1\| ABHD14B protein [Homo sapiens]	4.0E-29	[1..210]	[29..238]
gi\|147904364, gi... - gi\|50417776\|gb\|AAH78066.1\| Ephx2-prov protein [Xenopus laevis], gi\|147904364\|ref\|NP_001087143.1\| epo...	2.0E-28	[2..186]	[233..412]
gi\|182890020, gi... - gi\|56693357\|ref\|NP_001008642.1\| epoxide hydrolase 2, cytoplasmic [Danio rerio], gi\|56269293\|gb\|AAH86...	1.0E-27	[7..163]	[233..383]
gi\|62859673, gi\|... - gi\|62859673\|ref\|NP_001017276.1\| hypothetical protein LOC550030 [Xenopus (Silurana) tropicalis], gi\|1...	2.0E-27	[3..210]	[2..211]
gi\|109659347, gi... - gi\|115495833\|ref\|NP_001069002.1\| epoxide hydrolase 2, cytoplasmic [Bos taurus], gi\|109659347\|gb\|AAI1...	2.0E-27	[8..143]	[238..367]
ABHEB_RAT - Protein ABHD14B OS=Rattus norvegicus GN=Abhd14b PE=2 SV=1	2.0E-27	[3..209]	[2..209]
gi\|11262624, gi\|... - gi\|6562252\|emb\|CAB62622.1\| epoxide hydrolase-like protein [Arabidopsis thaliana], gi\|18491129\|gb\|AAL...	2.0E-27	[1..196]	[1..194]

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Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASVEQREG TIQVQGQALF FREALPGSGQ ARFSVLLLHG IRFSSETWQN LGTLHRLAQA  60
   61 GYRAVAIDLP GLGHSKEAAA PAPIGELAPG SFLAAVVDAL ELGPPVVISP SLSGMYSLPF 120
  121 LTAPGSQLPG FVPVAPICTD KINAANYASV KTPALIVYGD QDPMGQTSFE HLKQLPNHRV 180
  181 LIMKGAGHPC YLDKPEEWHT GLLDFLQGLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.0
Match:	1imjA
Description:	Ccg1/TafII250-interacting factor B (Cib)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.629869101256762	bayes_pls_golite062009
hydrolase activity	0.512422589119661	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: