YRC Public Data Repository - Protein Structure Prediction

Protein:	TUBB2B
Organism:	Homo sapiens
Length:	445 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TUBB2B.

Description	E-value	Query Range	Subject Range
gi\|48095525 - gi\|48095525\|ref\|XP_392313.1\| PREDICTED: similar to -Tubulin at 56D CG9277-PB, isoform B [Apis mellif...	0.0	[1..443]	[1..443]
gi\|91086093 - gi\|91086093\|ref\|XP_967267.1\| PREDICTED: similar to beta1-tubulin [Tribolium castaneum]	0.0	[1..443]	[1..443]
gi\|157767470 - gi\|157767470\|ref\|XP_001667215.1\| Hypothetical protein CBG16137 [Caenorhabditis briggsae AF16] tbb-4 - tubulin beta chain status:Partially_confirmed UniProt:P41937 protein_id:CAA86310.1 gi\|39596183, gi\|... - gi\|39596183\|emb\|CAE69820.1\| Hypothetical protein CBG16137 [Caenorhabditis briggsae], gi\|187026681\|em...	0.0	[1..444]	[1..444]
gi\|157132376, gi... - gi\|157132376\|ref\|XP_001656025.1\| tubulin beta chain [Aedes aegypti], gi\|108881720\|gb\|EAT45945.1\| tub...	0.0	[1..443]	[1..443]
gi\|74223737 - gi\|74223737\|dbj\|BAE28709.1\| unnamed protein product [Mus musculus]	0.0	[1..429]	[1..429]
gi\|73996516 - gi\|73996516\|ref\|XP_850665.1\| PREDICTED: similar to Tubulin alpha-2 chain (Alpha-tubulin 2) isoform 2...	0.0	[1..438]	[1..448]
TBB3_BOVIN - Tubulin beta-3 chain OS=Bos taurus GN=TUBB3 PE=1 SV=1 ENSMMUT000000391... - null, null TUBB4, TUBB3 - tubulin, beta 4, tubulin, beta 3 TBB3_MACFA - Tubulin beta-3 chain OS=Macaca fascicularis GN=TUBB3 PE=2 SV=1 gi\|57086939 - gi\|57086939\|ref\|XP_536745.1\| PREDICTED: similar to tubulin, beta 3 isoform 1 [Canis familiaris]	0.0	[1..445]	[1..446]
gi\|86451920 - gi\|86451920\|gb\|ABC97355.1\| beta tubulin [Streblomastix strix]	0.0	[1..433]	[1..433]

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Predicted Domain #1

Region A:
Residues: [1-445]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIVHIQAG QCGNQIGAKF WEVISDEHGI DPTGSYHGDS DLQLERINVY YNEATGNKYV  60
   61 PRAILVDLEP GTMDSVRSGP FGQIFRPDNF VFGQSGAGNN WAKGHYTEGA ELVDSVLDVV 120
  121 RKESESCDCL QGFQLTHSLG GGTGSGMGTL LISKIREEYP DRIMNTFSVM PSPKVSDTVV 180
  181 EPYNATLSVH QLVENTDETY CIDNEALYDI CFRTLKLTTP TYGDLNHLVS ATMSGVTTCL 240
  241 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRGSQQ YRALTVPELT QQMFDSKNMM 300
  301 AACDPRHGRY LTVAAIFRGR MSMKEVDEQM LNVQNKNSSY FVEWIPNNVK TAVCDIPPRG 360
  361 LKMSATFIGN STAIQELFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS 420
  421 EYQQYQDATA DEQGEFEEEE GEDEA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1ffxB
Description:	Tubulin:stathmin-like domain complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits