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View Structure Prediction Details

Protein: FGF9
Organism: Homo sapiens
Length: 208 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FGF9.

Description E-value Query
Range		 Subject
Range
FGF9_RAT - Fibroblast growth factor 9 OS=Rattus norvegicus GN=Fgf9 PE=2 SV=2
gi|1488392 - gi|1488392|gb|AAB36429.1| fibroblast growth factor 9; FGF9 [Mus sp.]
FGF9_MOUSE - Fibroblast growth factor 9 OS=Mus musculus GN=Fgf9 PE=2 SV=2
 8.0E-75 [1..208] [1..208]
FGF9_PIG - Fibroblast growth factor 9 OS=Sus scrofa GN=FGF9 PE=2 SV=1
 1.0E-74 [1..208] [1..208]
FGF9_MOUSE - Glia-activating factor OS=Mus musculus GN=Fgf9 PE=2 SV=1
 1.0E-74 [1..208] [1..208]
gi|76631618, gi|... - gi|76631620|ref|XP_877779.1| PREDICTED: similar to fibroblast growth factor 9 precursor isoform 2 [B...
 2.0E-74 [1..208] [1..208]
gi|45383362, gi|... - gi|45383362|ref|NP_989730.1| fibroblast growth factor 9 (glia-activating factor) [Gallus gallus], gi...
 2.0E-74 [1..208] [1..208]
FGF9_DIDAL - Fibroblast growth factor 9 OS=Didelphis albiventris GN=FGF9 PE=2 SV=1
 1.0E-72 [1..208] [1..209]
FGF9_XENLA - Fibroblast growth factor 9 OS=Xenopus laevis GN=fgf9 PE=2 SV=1
 4.0E-70 [1..208] [1..209]

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Predicted Domain #1
Region A:
Residues: [1-208] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPLGEVGNY FGVQDAVPFG NVPVLPVDSP VLLSDHLGQS EAGGLPRGPA VTDLDHLKGI  60
   61 LRRRQLYCRT GFHLEIFPNG TIQGTRKDHS RFGILEFISI AVGLVSIRGV DSGLYLGMNE 120
  121 KGELYGSEKL TQECVFREQF EENWYNTYSS NLYKHVDTGR RYYVALNKDG TPREGTRTKR 180
  181 HQKFTHFLPR PVDPDKVPEL YKDILSQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.69897
Match: 1ihkA
Description: Fibroblast growth factor 9, FGF9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fibroblast growth factor receptor binding 5.68976822724664 bayes_pls_golite062009
growth factor activity 5.6790632853895 bayes_pls_golite062009
receptor binding 4.8109037277027 bayes_pls_golite062009
cytokine activity 3.76931834545338 bayes_pls_golite062009
protein binding 2.99442649109752 bayes_pls_golite062009
binding 2.90110516688922 bayes_pls_golite062009
glycosaminoglycan binding 2.49177421879896 bayes_pls_golite062009
heparin binding 2.1616134585534 bayes_pls_golite062009
polysaccharide binding 1.81686028727894 bayes_pls_golite062009
pattern binding 0.839280621598109 bayes_pls_golite062009
interleukin-1 receptor binding 0.8084616632765 bayes_pls_golite062009
nerve growth factor receptor binding 0.308245352535379 bayes_pls_golite062009
interleukin-1, Type I receptor binding 0.234893926720301 bayes_pls_golite062009
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