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View Structure Prediction Details

Protein: ALG12
Organism: Homo sapiens
Length: 488 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALG12.

Description E-value Query
Range
Subject
Range
ALG12_MOUSE - Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase OS=Mus musculus GN=Alg12 PE=2 SV=2
0.0 [1..488] [1..486]
gi|22266724 - gi|22266724|gb|AAM94900.1|AF311904_1 membrane protein SB87 precursor [Homo sapiens]
0.0 [1..471] [1..471]
gi|114687013, gi... - gi|114687015|ref|XP_001140006.1| PREDICTED: asparagine-linked glycosylation 12 isoform 3 [Pan troglo...
0.0 [1..486] [1..486]
gi|220948018 - gi|220948018|gb|ACL86552.1| CG8412-PA [synthetic construct]
CG8412-PA - This gene is referred to in FlyBase by the symbol Dmel\CG8412 (CG8412, FBgn0037743). It is a protein...
0.0 [15..485] [3..479]
gi|109481118, gi... - gi|215276943|ref|NP_001101574.2| alpha-1,6-mannosyltransferase ALG12 [Rattus norvegicus], gi|1718467...
0.0 [1..488] [1..488]
gi|54638331, gi|... - gi|54638331|gb|EAL27733.1| GA21058-PA [Drosophila pseudoobscura], gi|125774667|ref|XP_001358592.1| G...
0.0 [16..484] [4..478]
gi|73968859 - gi|73968859|ref|XP_848418.1| PREDICTED: similar to alpha-1,6-mannosyltransferase ALG12 isoform 2 [Ca...
0.0 [13..488] [15..491]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGKGSSGRR PLLLGLLVAV ATVHLVICPY TKVEESFNLQ ATHDLLYHWQ DLEQYDHLEF  60
   61 PGVVPRTFLG PVVIAVFSSP AVYVLSLLEM SKFYSQLIVR GVLGLGVIFG LWTLQKEVRR 120
  121 HFGAMVATMF CWVTAMQFHL MFYCTRTLPN VLALPVVLLA LAAWLRHEWA RFIWLSAFAI 180
  181 IVFRVELCLF LGLLLLLALG NRKVSVVRAL RHAVPAGILC LGLTVAVDSY FWRQLTWP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [239-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGKVLWYNTV LNKSSNWGTS PLLWYFYSAL PRGLGCSLLF IPLGLVDRRT HAPTVLALGF  60
   61 MALYSLLPHK ELRFIIYAFP MLNITAARGC SYLLNNYKKS WLYKAGSLLV IGHLVVNAAY 120
  121 SATALYVSHF N

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [370-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPGGVAMQRL HQLVPPQTDV LLHIDVAAAQ TGVSRFLQVN SAWRYDKRED VQPGTGMLAY  60
   61 THILMEAAPG LLALYRDTHR VLASVVGTTG VSLNLTQLPP FNVHLQTKLV LLERLPRPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.592 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.470 a.7.8 GAT domain
View Download 0.440 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.660 a.7.5 Tubulin chaperone cofactor A
View Download 0.498 a.121.1 Tetracyclin repressor-like, C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle