YRC Public Data Repository - Protein Structure Prediction

Protein:	RPP25
Organism:	Homo sapiens
Length:	199 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPP25.

Description	E-value	Query Range	Subject Range
RPP25_RAT - Ribonuclease P protein subunit p25 OS=Rattus norvegicus GN=Rpp25 PE=2 SV=1	4.0E-73	[1..199]	[1..199]
RPP25_MOUSE - Ribonuclease P protein subunit p25 OS=Mus musculus GN=Rpp25 PE=2 SV=1	2.0E-72	[1..199]	[1..199]
gi\|194676854, gi... - gi\|76647232\|ref\|XP_609164.2\| PREDICTED: similar to ribonuclease P 25kDa subunit [Bos taurus], gi\|194...	2.0E-68	[1..199]	[12..210]
gi\|7020433, gi\|8... - gi\|8923355\|ref\|NP_060263.1\| ribonuclease P 25kDa subunit [Homo sapiens], gi\|7020433\|dbj\|BAA91128.1\| ...	3.0E-64	[1..199]	[1..199]
gi\|55642945 - gi\|55642945\|ref\|XP_510676.1\| PREDICTED: ribonuclease P 25kDa subunit [Pan troglodytes]	1.0E-62	[1..199]	[1..199]
gi\|109081919 - gi\|109081919\|ref\|XP_001101885.1\| PREDICTED: similar to ribonuclease P (predicted) [Macaca mulatta]	3.0E-62	[1..199]	[1..199]
CG9422-PC, CG942... - This gene is referred to in FlyBase by the symbol Dmel\CG9422 (CG9422, FBgn0033092). It is a protein...	1.0E-51	[1..191]	[1..186]
gi\|74001001 - gi\|74001001\|ref\|XP_854362.1\| PREDICTED: similar to ribonuclease P 25kDa subunit [Canis familiaris]	2.0E-51	[1..195]	[15..209]
gi\|8778978, gi\|2... - gi\|8778978\|gb\|AAF79893.1\|AC022472_2 Contains similarity to pigpen protein from Mus musculus gb\|AF224...	2.0E-51	[27..176]	[233..371]

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Predicted Domain #1

Region A:
Residues: [1-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENFRKVRSE EAPAGCGAEG GGPGSGPFAD LAPGAVHMRV KEGSKIRNLM AFATASMAQP  60
   61 ATRAIVFSGC GRATTKTVTC AEILKRRLAG LHQVTRLRYR SVREVWQSLP PGPTQGQTPG 120
  121 EPAASLSVLK NVPGLAILLS KDALDPRQPG YQPPNPHPGP SSPPAAPASK RSLGEPAAGE 180
  181 GSAKRSQPEP GVADEDQTA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.522879
Match:	1nfhA
Description:	Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits