YRC Public Data Repository - Protein Structure Prediction

Protein:	MED18
Organism:	Homo sapiens
Length:	208 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED18.

Description	E-value	Query Range	Subject Range
gi\|149024140, gi... - gi\|169234862\|ref\|NP_001108509.1\| hypothetical protein LOC682988 [Rattus norvegicus], gi\|165971258\|gb... tr\|G3H1Z1\|G3H1Z1... - Mediator of RNA polymerase II transcription subunit 18 OS=Cricetulus griseus GN=I79_004190 PE=4 SV=1	1.0E-96	[1..208]	[1..208]
tr\|M3WIT0\|M3WIT0... - Mediator complex subunit 18 OS=Felis catus GN=MED18 PE=4 SV=1 gi\|57044032 - gi\|57044032\|ref\|XP_544460.1\| PREDICTED: similar to mediator of RNA polymerase II transcription, subu...	2.0E-96	[1..208]	[1..208]
MED18_MOUSE - Mediator of RNA polymerase II transcription subunit 18 OS=Mus musculus GN=Med18 PE=1 SV=1	2.0E-96	[1..208]	[1..208]
gi\|7019886, gi\|8... - gi\|8923053\|ref\|NP_060108.1\| mediator complex subunit 18 [Homo sapiens], gi\|7019886\|dbj\|BAA90910.1\| u...	3.0E-96	[1..208]	[1..208]
gi\|109000141 - gi\|109000141\|ref\|XP_001113062.1\| PREDICTED: similar to mediator of RNA polymerase II transcription, ... CCDS322.1_1 - null	3.0E-96	[1..208]	[1..208]
MED18_BOVIN - Mediator of RNA polymerase II transcription subunit 18 OS=Bos taurus GN=MED18 PE=2 SV=1	4.0E-96	[1..208]	[1..208]
MED18_DANRE - Mediator of RNA polymerase II transcription subunit 18 OS=Danio rerio GN=med18 PE=2 SV=1	2.0E-92	[1..208]	[1..208]
MED18_XENTR - Mediator of RNA polymerase II transcription subunit 18 OS=Xenopus tropicalis GN=med18 PE=2 SV=1	2.0E-87	[1..208]	[1..208]

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Predicted Domain #1

Region A:
Residues: [1-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAPPVTMMP VTGGTINMME YLLQGSVLDH SLESLIHRLR GLCDNMEPET FLDHEMVFLL  60
   61 KGQQASPFVL RARRSMDRAG APWHLRYLGQ PEMGDKNRHA LVRNCVDIAT SENLTDFLME 120
  121 MGFRMDHEFV AKGHLFRKGI MKIMVYKIFR ILVPGNTDST EALSLSYLVE LSVVAPAGQD 180
  181 MVSDDMKNFA EQLKPLVHLE KIDPKRLM

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.951
Match:	2fjtA
Description:	No description for 2fjtA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits