YRC Public Data Repository - Protein Structure Prediction

Protein:	C8orf30A
Organism:	Homo sapiens
Length:	390 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C8orf30A.

Description	E-value	Query Range	Subject Range
gi\|109087722 - gi\|109087722\|ref\|XP_001090013.1\| PREDICTED: similar to brain protein 16 [Macaca mulatta]	0.0	[1..390]	[1..396]
h0024591 - null C8orf30B - chromosome 8 open reading frame 30B	0.0	[17..390]	[17..390]
HGH1_MOUSE - Protein HGH1 homolog OS=Mus musculus GN=Hgh1 PE=1 SV=1	0.0	[1..359]	[1..366]
HGH1_RAT - Protein HGH1 homolog OS=Rattus norvegicus GN=Hgh1 PE=2 SV=1	0.0	[1..361]	[1..368]
gi\|114622172 - gi\|114622172\|ref\|XP_520011.2\| PREDICTED: similar to Chromosome 8 open reading frame 30A [Pan troglod...	0.0	[17..390]	[17..395]
gi\|76633964 - gi\|76633964\|ref\|XP_586006.2\| PREDICTED: similar to brain protein 16 [Bos taurus]	0.0	[15..390]	[3..385]
gi\|42552623, gi\|... - gi\|46121703\|ref\|XP_385406.1\| hypothetical protein FG05230.1 [Gibberella zeae PH-1], gi\|42552623\|gb\|E...	0.0	[20..375]	[3..372]
gi\|55233907, gi\|... - gi\|58396135\|ref\|XP_321688.2\| ENSANGP00000015209 [Anopheles gambiae str. PEST], gi\|55233907\|gb\|EAA017...	0.0	[22..356]	[4..341]

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Predicted Domain #1

Region A:
Residues: [1-390]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEAGAGAGA SGGPEASPEA EVVKLLPFLA PGARADLQAA AVRHVLALTG CGPGRALLAG  60
   61 QAALLQALME LAPASAPARD AARALVNLAA DPGLHETLLA ADPGLPARLM GRALDPQWPW 120
  121 AEEAAAALAN LSREPAPCAA LMAALAAAEP ADSGLERLVR ALCTPGYNAR APLHYLAPLL 180
  181 SNLSQRPAAR AFLLDPDRCV VQRLLPLTQY PDSSVRRGGV VGTLRNCCFE HRHHEWLLGP 240
  241 EVDILPFLLL PLAGPEDFSE EEMERLPVDL QYLPPDKQRE PDADIRKMLV EAIMLLTATA 300
  301 PGRQQVRDQG AYLILRELHS WEPEPDVRTA CEKLIQVLIG DEPERGMENL LEVQVPEDVE 360
  361 QQLQQLDCRE QEQLERELAP EPWVERATPT

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.96
Match:	1wa5B
Description:	Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.680981594654886	bayes_pls_golite062009
protein binding	0.147845980108289	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: