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View Structure Prediction Details

Protein: RGS20
Organism: Homo sapiens
Length: 388 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RGS20.

Description E-value Query
Range
Subject
Range
gi|114620123 - gi|114620123|ref|XP_001151118.1| PREDICTED: regulator of G-protein signalling 20 isoform 4 [Pan trog...
0.0 [1..388] [1..388]
gi|109086397 - gi|109086397|ref|XP_001082409.1| PREDICTED: regulator of G-protein signalling 20 isoform 3 [Macaca m...
0.0 [1..388] [1..394]
gi|73999107 - gi|73999107|ref|XP_848801.1| PREDICTED: similar to Regulator of G-protein signaling 20 (RGS20) (Regu...
0.0 [1..388] [1..381]
RGS20_BOVIN - Regulator of G-protein signaling 20 OS=Bos taurus GN=RGS20 PE=1 SV=2
0.0 [1..388] [1..374]
gi|109476071 - gi|109476071|ref|XP_001068374.1| PREDICTED: similar to Regulator of G-protein signaling 20 (RGS20) (...
4.0E-84 [51..388] [137..471]
gi|20977052 - gi|20977052|gb|AAM33253.1|AF490838_1 RGS3 isoform RGS3S [Homo sapiens]
2.0E-73 [103..384] [3..308]
gi|4581016 - gi|4581016|gb|AAD24580.1|AF130744_1 regulator of G-protein signalling LOCO C2 [Drosophila melanogast...
6.0E-73 [56..384] [272..583]

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Predicted Domain #1
Region A:
Residues: [1-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQLSQDNQE CLQKHFSRPS IWTQFLPLFR AQRYNTDIHQ ITENEGDLRA VPDIKSFPPA  60
   61 QLPDSPAAPK LFGLLSSPLS SLARFFSHLL RRPPPEAPRR RLDFSPLLPA LPAARLSRGH 120
  121 EELPGRLSLL LGAALALPGR PSGGRPLRPP HPVAKPREED ATAGQSSPMP QMGSERMEMR 180
  181 KRQMPAAQDT PGAAPGQPGA GSRGSNACCF CWCCCCSCSC LTVRNQEDQR PTIASHELRA 240
  241 DL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [243-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTWEESPAPT LEEVNAWAQS FDKLMVTPAG RNAFREFLRT EFSEENMLFW MACEELKKEA  60
   61 NKNIIEEKAR IIYEDYISIL SPKEVSLDSR VREVINRNMV EPSQHIFDDA QLQIYTLMHR 120
  121 DSYPRFMNSA VYKDLLQSLS EKSIEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.522879
Match: 1zv4X
Description: Structure of the Regulator of G-Protein Signaling 17 (RGSZ2)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle