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View Structure Prediction Details

Protein: FOS
Organism: Homo sapiens
Length: 380 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOS.

Description E-value Query
Range
Subject
Range
gi|4581531, gi|1... - gi|4581531|emb|CAB40144.1| c-Fos protein [Sus scrofa], gi|178057282|ref|NP_001116585.1| v-fos FBJ mu...
4.0E-74 [1..380] [1..380]
gi|60827174, gi|... - gi|61368263|gb|AAX43142.1| v-fos FBJ murine osteosarcoma viral oncogene-like [synthetic construct], ...
4.0E-73 [1..380] [1..380]
FOS_MOUSE - Proto-oncogene c-Fos OS=Mus musculus GN=Fos PE=1 SV=1
4.0E-73 [1..380] [1..380]
gi|146741218, gi... - gi|148528980|ref|NP_001091891.1| v-fos FBJ murine osteosarcoma viral oncogene homolog [Pan troglodyt...
5.0E-73 [1..380] [1..380]
gi|57090755 - gi|57090755|ref|XP_547914.1| PREDICTED: similar to Proto-oncogene protein c-fos (Cellular oncogene f...
5.0E-73 [1..380] [1..380]
FOS_FELCA - Proto-oncogene c-Fos OS=Felis catus GN=FOS PE=2 SV=1
6.0E-73 [1..380] [1..381]
FOS_RAT - Proto-oncogene c-Fos OS=Rattus norvegicus GN=Fos PE=1 SV=1
gi|55934 - gi|55934|emb|CAA29937.1| unnamed protein product [Rattus rattus]
8.0E-73 [1..380] [1..380]
FOS_BOVIN - Proto-oncogene c-Fos OS=Bos taurus GN=FOS PE=2 SV=2
2.0E-72 [1..380] [1..380]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMFSGFNADY EASSSRCSSA SPAGDSLSYY HSPADSFSSM GSPVNAQDFC TDLAVSSANF  60
   61 IPTVTAISTS PDLQWLVQPA LVSSVAPSQT RAPHPFGVPA PSAGAYSRAG VVKTMTGGRA 120
  121 Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [122-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIGRRGKVEQ LSPEEEEKRR IRRERNKMAA AKCRNRRREL TDTLQAETDQ LEDEKSALQT  60
   61 EIANLLKEKE KLEFILAAHR PACKIPDDLG FPEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 1fosE
Description: C-fos
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [216-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVASLDLTG GLPEVATPES EEAFTLPLLN DPEPKPSVEP VKSISSMELK TEPFDDFLFP  60
   61 ASSRPSGSET ARSVPDMDLS GSFYAADWEP LHSGSLGMGP MATELEPLCT PVVTCTPSCT 120
  121 AYTSSFVFTY PEADSFPSCA AAHRKGSSSN EPSSDSLSSP TLLAL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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