YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: AMPH
Organism: Homo sapiens
Length: 695 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMPH.

Description E-value Query
Range
Subject
Range
gi|61364658 - gi|61364658|gb|AAX42580.1| amphiphysin [synthetic construct]
0.0 [1..695] [1..695]
gi|109066800 - gi|109066800|ref|XP_001100126.1| PREDICTED: amphiphysin isoform 2 [Macaca mulatta]
0.0 [1..695] [1..694]
gi|21707930 - gi|21707930|gb|AAH34376.1| Amphiphysin [Homo sapiens]
0.0 [1..695] [1..695]
AMPH_MOUSE - Amphiphysin OS=Mus musculus GN=Amph PE=1 SV=1
0.0 [1..695] [1..686]
AMPH_RAT - Amphiphysin OS=Rattus norvegicus GN=Amph PE=1 SV=1
0.0 [1..695] [1..683]
AMPH_CHICK - Amphiphysin OS=Gallus gallus GN=AMPH PE=2 SV=1
0.0 [1..695] [1..682]
gi|148229419, gi... - gi|47939999|gb|AAH72364.1| MGC83546 protein [Xenopus laevis], gi|148229419|ref|NP_001085079.1| hypot...
0.0 [8..695] [12..666]

Back

Predicted Domain #1
Region A:
Residues: [1-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADIKTGIFA KNVQKRLNRA QEKVLQKLGK ADETKDEQFE EYVQNFKRQE AEGTRLQREL  60
   61 RGYLAAIKGM QEASMKLTES LHEVYEPDWY GREDVKMVGE KCDVLWEDFH QKLVDGSLLT 120
  121 LDTYLGQFPD IKNRIAKRSR KLVDYDSARH HLEALQSSKR KDESRISKAE EEFQKAQKVF 180
  181 EEFNVDLQEE LPSLWSRRVG FYVNTFKNVS SLEAKFHKEI AVLCHKLYEV MTKLGDQHAD 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.39794
Match: 2ficA
Description: No description for 2ficA was found.

Predicted Domain #2
Region A:
Residues: [241-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAFTIQGAPS DSGPLRIAKT PSPPEEPSPL PSPTASPNHT LAPASPAPAR PRSPSQTRKG  60
   61 PPVPPLPKVT PTKELQQENI ISFFEDNFVP EISVTTPSQN EVPEVKKEET LLDLDFDPFK 120
  121 PEVTPAGSAG VTHSPMSQTL PWDLWTTSTD LVQPASGGSF NG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.17
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [403-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTQPQDTSLF TMQTDQSMIC NLAESEQAPP TEPKAEEPLA AVTPAVGLDL GMDTRAEEPV  60
   61 EEAVIIPGAD ADAAVGTLVS AAEGAPGEEA EAEKATV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [500-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAGEGVSLEE AKIGTETTEG AESAQPEAEE LEATVPQEKV IPSVVIEPAS NHEEEGENEI  60
   61 TIGAEPKETT EDAAPPGPTS ETPELATEQK PIQDPQPTPS APAMGAADQL ASAREASQEL 120
  121 PPGFLYKVET LHDFEAANSD ELTLQRGDVV LVVPSDSEAD QDAGWLVGVK ESDWLQYRDL 180
  181 ATYKGLFPEN FTRRLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 1mv3A
Description: NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle