| Protein: | ESYT1 |
| Organism: | Homo sapiens |
| Length: | 1104 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESYT1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1104] | [1..1104] |
|
|
0.0 | [1..1104] | [1..1104] |
|
|
0.0 | [1..1104] | [1..1092] |
|
|
0.0 | [1..1104] | [1..1104] |
|
|
0.0 | [1..1104] | [1..1088] |
|
|
0.0 | [43..1104] | [1..1072] |
|
Region A: Residues: [1-129] |
1 11 21 31 41 51
| | | | | |
1 MERSPGEGPS PSPMDQPSAP SDPTDQPPAA HAKPDPGSGG QPAGPGAAGE ALAVLTSFGR 60
61 RLLVLIPVYL AGAVGLSVGF VLFGLALYLG WRRVRDEKER SLRAARQLLD DEEQLTAKTL 120
121 YMSHRELPA
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [130-314] |
1 11 21 31 41 51
| | | | | |
1 WVSFPDVEKA EWLNKIVAQV WPFLGQYMEK LLAETVAPAV RGSNPHLQTF TFTRVELGEK 60
61 PLRIIGVKVH PGQRKEQILL DLNISYVGDV QIDVEVKKYF CKAGVKGMQL HGVLRVILEP 120
121 LIGDLPFVGA VSMFFIRRPT LDINWTGMTN LLDIPGLSSL SDTMIMDSIA AFLVLPNRLL 180
181 VPLVP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [315-577] |
1 11 21 31 41 51
| | | | | |
1 DLQDVAQLRS PLPRGIIRIH LLAARGLSSK DKYVKGLIEG KSDPYALVRL GTQTFCSRVI 60
61 DEELNPQWGE TYEVMVHEVP GQEIEVEVFD KDPDKDDFLG RMKLDVGKVL QASVLDDWFP 120
121 LQGGQGQVHL RLEWLSLLSD AEKLEQVLQW NWGVSSRPDP PSAAILVVYL DRAQDLPLKK 180
181 GNKEPNPMVQ LSIQDVTQES KAVYSTNCPV WEEAFRFFLQ DPQSQELDVQ VKDDSRALTL 240
241 GALTLPLARL LTAPELILDQ WFQ
|
| Detection Method: | |
| Confidence: | 44.522879 |
| Match: | 1dqvA |
| Description: | Synaptogamin I |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [578-757] |
1 11 21 31 41 51
| | | | | |
1 LSSSGPNSRL YMKLVMRILY LDSSEICFPT VPGCPGAWDV DSENPQRGSS VDAPPRPCHT 60
61 TPDSQFGTEH VLRIHVLEAQ DLIAKDRFLG GLVKGKSDPY VKLKLAGRSF RSHVVREDLN 120
121 PRWNEVFEVI VTSVPGQELE VEVFDKDLDK DDFLGRCKVR LTTVLNSGFL DEWLTLEDVP 180
181
|
| Detection Method: | |
| Confidence: | 27.30103 |
| Match: | 1djgA |
| Description: | Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| catalytic activity | 0.693222330136336 | bayes_pls_golite062009 |
| hydrolase activity | 0.17768980721334 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.05056572092175 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 0.0304825793447705 | bayes_pls_golite062009 |
| phosphoric diester hydrolase activity | 0.01534375493934 | bayes_pls_golite062009 |
|
Region A: Residues: [758-964] |
1 11 21 31 41 51
| | | | | |
1 SGRLHLRLER LTPRPTAAEL EEVLQVNSLI QTQKSAELAA ALLSIYMERA EDLPLRKGTK 60
61 HLSPYATLTV GDSSHKTKTI SQTSAPVWDE SASFLIRKPH TESLELQVRG EGTGVLGSLS 120
121 LPLSELLVAD QLCLDRWFTL SSGQGQVLLR AQLGILVSQH SGVEAHSHSY SHSSSSLSEE 180
181 PELSGGPPHI TSSAPELRQR LTHVDSP
|
| Detection Method: | |
| Confidence: | 5.37 |
| Match: | 2nq3A |
| Description: | No description for 2nq3A was found. |
| Term | Confidence | Notes |
| binding | 0.00485162528958194 | bayes_pls_golite062009 |
|
Region A: Residues: [965-1104] |
1 11 21 31 41 51
| | | | | |
1 LEAPAGPLGQ VKLTLWYYSE ERKLVSIVHG CRSLRQNGRD PPDPYVSLLL LPDKNRGTKR 60
61 RTSQKKRTLS PEFNERFEWE LPLDEAQRRK LDVSVKSNSS FMSRERELLG KVQLDLAETD 120
121 LSQGVARWYD LMDNKDKGSS
|
| Detection Method: | |
| Confidence: | 24.69897 |
| Match: | 2dmgA |
| Description: | No description for 2dmgA was found. |
