YRC Public Data Repository - Protein Structure Prediction

Protein:	MAPK7
Organism:	Homo sapiens
Length:	816 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAPK7.

Description	E-value	Query Range	Subject Range
gi\|973307, gi\|97... - gi\|973311\|gb\|AAA82933.1\| BMK1 gamma kinase, gi\|973309\|gb\|AAA82932.1\| BMK1 beta kinase, gi\|973307\|gb\|...	0.0	[1..816]	[1..816]
gi\|109113589, gi... - gi\|109113595\|ref\|XP_001099621.1\| PREDICTED: similar to mitogen-activated protein kinase 7 isoform 1 ...	0.0	[1..816]	[1..816]
gi\|74199112 - gi\|74199112\|dbj\|BAE33103.1\| unnamed protein product [Mus musculus]	3.0E-96	[1..816]	[1..810]
gi\|12698876, gi\|... - gi\|218192578\|gb\|EEC75005.1\| hypothetical protein OsI_11072 [Oryza sativa Indica Group], gi\|12698876\|...	2.0E-79	[30..394]	[10..369]
MPK5_ORYSA - Mitogen-activated protein kinase 5 (EC 2.7.11.24) (MAP kinase 5) (OsMAPK5) (OsMAP1) (Benzothiadiazol... MPK5_ORYSJ - Mitogen-activated protein kinase 5 OS=Oryza sativa subsp. japonica GN=MPK5 PE=1 SV=1 MPK5_ORYSI - Mitogen-activated protein kinase 5 OS=Oryza sativa subsp. indica GN=MPK5 PE=1 SV=2	2.0E-79	[30..394]	[10..369]

Back

Predicted Domain #1

Region A:
Residues: [1-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPLKEEDG EDGSAEPPGP VKAEPAHTAA SVAAKNLALL KARSFDVTFD VGDEYEIIET  60
   61 IGNGAYGVVS SARRRLTGQQ VAIKKIPNAF DVVTNAKRTL RELKILKHFK HDNIIAIKDI 120
  121 LRPTVPYGEF KSVYVVLDLM ESDLHQIIHS SQPLTLEHVR YFLYQLLRGL KYMHSAQVIH 180
  181 RDLKPSNLLV NENCELKIGD FGMARGLCTS PAEHQYFMTE YVATRWYRAP ELMLSLHEYT 240
  241 QAIDLWSVGC IFGEMLARRQ LFPGKNYVHQ LQLIMMVLGT PSPAVIQAVG AERVRAYIQS 300
  301 LPPRQPVPWE TVYPGADRQA LSLLGRMLRF EPSARISAAA ALRHPFLAKY HDPDDEPDCA 360
  361 PPFDFAFDRE ALTRERIKEA IVAEIEDFHA RREGIRQQIR FQPSLQPVAS EPGCPDVEMP 420
  421 SPWAPSGDCA MESPPPAPPP CPGPAPDTI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.39794
Match:	2gphA
Description:	No description for 2gphA was found.

Predicted Domain #2

Region A:
Residues: [450-669]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLTLQPPPPV SEPAPPKKDG AISDNTKAAL KAALLKSLRS RLRDGPSAPL EAPEPRKPVT  60
   61 AQERQREREE KRRRRQERAK EREKRRQERE RKERGAGASG GPSTDPLAGL VLSDNDRSLL 120
  121 ERWTRMARPA APALTSVPAP APAPTPTPTP VQPTSPPPGP VAQPTGPQPQ SAGSTSGPVP 180
  181 QPACPPPGPA PHPTGPPGPI PVPAPPQIAT STSLLAAQSL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [670-816]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPPPGLPGSS TPGVLPYFPP GLPPPDAGGA PQSSMSESPD VNLVTQQLSK SQVEDPLPPV  60
   61 FSGTPKGSGA GYGVGFDLEE FLNQSFDMGV ADGPQDGQAD SASLSASLLA DWLEGHGMNP 120
  121 ADIESLQREI QMDSPMLLAD LPDLQDP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits