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View Structure Prediction Details

Protein: B3GAT1
Organism: Homo sapiens
Length: 334 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for B3GAT1.

Description E-value Query
Range
Subject
Range
gi|2217942, gi|1... - gi|2217942|dbj|BAA20551.1| glycoprotein specific UDP-glucuronyltransferase [Rattus norvegicus], gi|1...
0.0 [1..334] [14..347]
gi|19071864, gi|... - gi|26349909|dbj|BAC38594.1| unnamed protein product [Mus musculus], pir||JC7828 glucuronyltransferas...
0.0 [1..334] [14..347]
gi|109109379 - gi|109109379|ref|XP_001083698.1| PREDICTED: similar to beta-1,3-glucuronyltransferase 1 [Macaca mula...
0.0 [1..334] [1..334]
B3GAT1 - beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
0.0 [1..334] [1..334]
B3GA1_CANLF - Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 OS=Canis lupus familiaris GN=B3G...
0.0 [1..334] [1..335]
B3GA1_PANTR - Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 OS=Pan troglodytes GN=B3GAT1 PE=...
0.0 [1..334] [1..332]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRRDILAI VLIVLPWTLL ITVWHQSTLA PLLAVHKDEG SDPRRETPPG ADPREYCTSD  60
   61 RDIVEVVRTE YVYTRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.453 a.4.1 Homeodomain-like
View Download 0.329 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.307 a.4.5 "Winged helix" DNA-binding domain
View Download 0.257 a.4.1 Homeodomain-like
View Download 0.251 d.58.25 Killer toxin KP6 alpha-subunit

Predicted Domain #2
Region A:
Residues: [77-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPWSDTLPTI HVVTPTYSRP VQKAELTRMA NTLLHVPNLH WLVVEDAPRR TPLTARLLRD  60
   61 TGLNYTHLHV ETPRNYKLRG DARDPRIPRG TMQRNLALRW LRETFPRNSS QPGVVYFADD 120
  121 DNTYSLELFE EMRSTRRVSV WPVAFVGGLR YEAPRVNGAG KVVGWKTVFD PHRPFAIDMA 180
  181 GFAVNLRLIL QRSQAYFKLR GVKGGYQESS LLRELVTLND LEPKAANCTK ILVWHTRTEK 240
  241 PVLVNEGKKG FTDPSVEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 115.0
Match: 1v82A
Description: Crystal structure of human GlcAT-P apo form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring hexosyl groups 4.49413422196176 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 4.10932284832375 bayes_pls_golite062009
UDP-glycosyltransferase activity 4.08451171179562 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 3.92716720753569 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.60650378115696 bayes_pls_golite062009
mannosyltransferase activity 2.3790353113186 bayes_pls_golite062009
nucleotidyltransferase activity 1.92166853180381 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
transferase activity 1.39859835180302 bayes_pls_golite062009
glucuronosyltransferase activity 0.95636156520578 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 0.565463388197361 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.412018910498896 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.350354864477855 bayes_pls_golite062009
uridylyltransferase activity 0.321928989676507 bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity 0.2363835251362 bayes_pls_golite062009
cytidylyltransferase activity 0.218759888732981 bayes_pls_golite062009
UDP-galactosyltransferase activity 0.10185872015123 bayes_pls_golite062009
galactosyltransferase activity 0.0931461042017721 bayes_pls_golite062009
guanylyltransferase activity 0.0539392112504681 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle