YRC Public Data Repository - Protein Structure Prediction

Protein:	MSH5
Organism:	Homo sapiens
Length:	834 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSH5.

Description	E-value	Query Range	Subject Range
gi\|91227833, gi\|... - gi\|91227833\|ref\|ZP_01262006.1\| DNA mismatch repair protein [Vibrio alginolyticus 12G01], gi\|91188343...	0.0	[1..832]	[80..848]
gi\|125617373, gi... - gi\|75829241\|ref\|ZP_00758551.1\| COG0249: Mismatch repair ATPase (MutS family) [Vibrio cholerae MO10],... gi\|229353916, gi... - gi\|229508991\|ref\|ZP_04398479.1\| DNA mismatch repair protein MutS [Vibrio cholerae B33], gi\|229353916... MUTS_VIBCH - DNA mismatch repair protein mutS OS=Vibrio cholerae GN=mutS PE=3 SV=1 MUTS_VIBCH - DNA mismatch repair protein MutS OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N1... gi\|75815683 - gi\|75815683\|ref\|ZP_00746180.1\| COG0249: Mismatch repair ATPase (MutS family) [Vibrio cholerae V52] MUTS_VIBCM - DNA mismatch repair protein MutS OS=Vibrio cholerae serotype O1 (strain M66-2) GN=mutS PE=3 SV=1 gi\|229507146, gi... - gi\|229507146\|ref\|ZP_04396652.1\| DNA mismatch repair protein MutS [Vibrio cholerae BX 330286], gi\|229... gi\|229344348, gi... - gi\|229519659\|ref\|ZP_04409102.1\| DNA mismatch repair protein MutS [Vibrio cholerae RC9], gi\|229344348... MUTS_VIBC3 - DNA mismatch repair protein MutS OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa... gi\|153223827, gi... - gi\|153223827\|ref\|ZP_01954082.1\| DNA mismatch repair protein MutS [Vibrio cholerae MAK 757], gi\|12411... gi\|126510344, gi... - gi\|153819112\|ref\|ZP_01971779.1\| DNA mismatch repair protein MutS [Vibrio cholerae NCTC 8457], gi\|126...	0.0	[1..828]	[88..853]
gi\|254850775, gi... - gi\|254850775\|ref\|ZP_05240125.1\| DNA mismatch repair protein MutS [Vibrio cholerae MO10], gi\|25484648... gi\|229368830, gi... - gi\|229606175\|ref\|YP_002876823.1\| DNA mismatch repair protein MutS [Vibrio cholerae MJ-1236], gi\|2293... tr\|C6YK41\|C6YK41... - DNA mismatch repair protein MutS OS=Vibrio cholerae MO10 GN=mutS PE=3 SV=1 gi\|75825907 - gi\|75825907\|ref\|ZP_00755342.1\| COG0249: Mismatch repair ATPase (MutS family) [Vibrio cholerae O395]	0.0	[1..828]	[105..870]
gi\|116219810, gi... - gi\|75819256\|ref\|ZP_00749345.1\| COG0249: Mismatch repair ATPase (MutS family) [Vibrio cholerae V51], ...	0.0	[1..828]	[105..870]
gi\|116183530, gi... - gi\|75854083\|ref\|ZP_00761802.1\| COG0249: Mismatch repair ATPase (MutS family) [Vibrio sp. Ex25], gi\|1...	0.0	[1..832]	[71..839]
MUTS_VIBPA - DNA mismatch repair protein MutS OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=... MUTS_VIBPA - DNA mismatch repair protein mutS OS=Vibrio parahaemolyticus GN=mutS PE=3 SV=1	0.0	[1..832]	[80..848]
MUTS_PHOPR - DNA mismatch repair protein MutS OS=Photobacterium profundum (strain SS9) GN=mutS PE=3 SV=1 MUTS_PHOPR - DNA mismatch repair protein MutS OS=Photobacterium profundum GN=mutS PE=3 SV=1	0.0	[1..832]	[82..851]
gi\|90327083, gi\|... - gi\|90412105\|ref\|ZP_01220112.1\| DNA mismatch repair protein [Photobacterium profundum 3TCK], gi\|90327...	0.0	[1..832]	[71..840]
gi\|75823717, gi\|... - gi\|75823717\|ref\|ZP_00753201.1\| COG0249: Mismatch repair ATPase (MutS family) [Vibrio cholerae RC385]...	0.0	[1..828]	[105..870]
MUTS_ERWCT - DNA mismatch repair protein mutS OS=Erwinia carotovora subsp. atroseptica GN=mutS PE=3 SV=1 MUTS_PECAS - DNA mismatch repair protein MutS OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN...	0.0	[1..834]	[85..854]

Back

Predicted Domain #1

Region A:
Residues: [1-834]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLGANPRR TPQGPRPGAA SSGFPSPAPV PGPREAEEEE VEEEEELAEI HLCVLWNSGY  60
   61 LGIAYYDTSD STIHFMPDAP DHESLKLLQR VLDEINPQSV VTSAKQDENM TRFLGKLASQ 120
  121 EHREPKRPEI IFLPSVDFGL EISKQRLLSG NYSFIPDAMT ATEKILFLSS IIPFDCLLTV 180
  181 RALGGLLKFL GRRRIGVELE DYNVSVPILG FKKFMLTHLV NIDQDTYSVL QIFKSESHPS 240
  241 VYKVASGLKE GLSLFGILNR CHCKWGEKLL RLWFTRPTHD LGELSSRLDV IQFFLLPQNL 300
  301 DMAQMLHRLL GHIKNVPLIL KRMKLSHTKV SDWQVLYKTV YSALGLRDAC RSLPQSIQLF 360
  361 RDIAQEFSDD LHHIASLIGK VVDFEGSLAE NRFTVLPNID PEIDEKKRRL MGLPSFLTEV 420
  421 ARKELENLDS RIPSCSVIYI PLIGFLLSIP RLPSMVEASD FEINGLDFMF LSEEKLHYRS 480
  481 ARTKELDALL GDLHCEIRDQ ETLLMYQLQC QVLARAAVLT RVLDLASRLD VLLALASAAR 540
  541 DYGYSRPRYS PQVLGVRIQN GRHPLMELCA RTFVPNSTEC GGDKGRVKVI TGPNSSGKSI 600
  601 YLKQVGLITF MALVGSFVPA EEAEIGAVDA IFTRIHSCES ISLGLSTFMI DLNQVAKAVN 660
  661 NATAQSLVLI DEFGKGTNTV DGLALLAAVL RHWLARGPTC PHIFVATNFL SLVQLQLLPQ 720
  721 GPLVQYLTME TCEDGNDLVF FYQVCEGVAK ASHASHTAAQ AGLPDKLVAR GKEVSDLIRS 780
  781 GKPIKPVKDL LKKNQMENCQ TLVDKFMKLD LEDPNLDLNV FMSQEVLPAA TSIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	169.0
Match:	1wb9A
Description:	Crystal Structure of E. coli DNA Mismatch Repair enzyme MutS, E38T mutant, in complex with a G.T mismatch
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits