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View Structure Prediction Details

Protein: gi|2662099
Organism: Homo sapiens
Length: 464 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2662099.

Description E-value Query
Range
Subject
Range
RRP8_RAT - Ribosomal RNA-processing protein 8 OS=Rattus norvegicus GN=Rrp8 PE=1 SV=1
2.0E-55 [9..464] [1..457]
gi|74186190, gi|... - gi|74186190|dbj|BAE42891.1| unnamed protein product [Mus musculus], gi|74182507|dbj|BAE42874.1| unna...
7.0E-55 [9..464] [1..457]
gi|114636509 - gi|114636509|ref|XP_508260.2| PREDICTED: similar to KIAA0409 [Pan troglodytes]
7.0E-53 [1..464] [32..495]
gi|109107525 - gi|109107525|ref|XP_001100895.1| PREDICTED: similar to T07A9.8 [Macaca mulatta]
2.0E-51 [2..464] [22..484]
RRP8 - ribosomal RNA processing 8, methyltransferase, homolog (yeast)
gi|168278607 - gi|168278607|dbj|BAG11183.1| KIAA0409 protein [synthetic construct]
4.0E-51 [9..464] [1..456]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDPALPTLMF EEPEWAEAAP VAAGLGPVIS RPPPAASSQN KGSKRRQLLA TLRALEAASL  60
   61 SQHPPSLCIS DSEEEEEERK KKCPKKASFA SASAEVGKKG KKKCQKQGPP CSDSEEEVER 120
  121 KKKCHKQALV GSDSAEDEKR KRKCQKHAPI NSAQHLDNVD QTGPKAWKGS TTNDPPKQSP 180
  181 GSTSPKPPHT LSRKQWRNRQ KNKRRCKNKF QPPQV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [216-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDQAPAEAPT EKTEVSPVPR TDSHEARAGA LRARMAQRLD GARFRYLNEQ LYSGPSSAAQ  60
   61 RLFQEDPEAF LLYHRGFQSQ VKKWPLQPVD RIARDLRQRP ASLVVADFGC GDCRLASSIR 120
  121 NPVHCFDLAS LDPRVTVCDM AQVPLEDESV DVAVFCLSLM GTNIRDFLEE ANRVLKPGGL 180
  181 LKVAEVSSRF EDVRTFLRAV TKLGFKIVSK DLTNSHFFLF DFQKTGPPLV GPKAQLSGLQ 240
  241 LQPCLYKRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 1ufkA
Description: Crystal structure of TT0836
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.723277178398499 bayes_pls_golite062009
transferase activity 0.64512166557639 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.54403439349476 bayes_pls_golite062009
methyltransferase activity 0.54389223881989 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle