YRC Public Data Repository - Protein Structure Prediction

Protein:	GJB1
Organism:	Homo sapiens
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GJB1.

Description	E-value	Query Range	Subject Range
gi\|22138847 - gi\|22138847\|dbj\|BAC07263.1\| connexin32 [Cavia porcellus]	0.0	[1..283]	[1..283]
gi\|57112205, gi\|... - gi\|74007614\|ref\|XP_857573.1\| PREDICTED: similar to Gap junction beta-1 protein (Connexin 32) (Cx32) ... tr\|M3WLD3\|M3WLD3... - Gap junction protein OS=Felis catus GN=GJB1 PE=3 SV=1	0.0	[1..283]	[1..283]
CXB1_HORSE - Gap junction beta-1 protein OS=Equus caballus GN=GJB1 PE=2 SV=1	0.0	[1..283]	[1..283]
CXB1_BOVIN - Gap junction beta-1 protein OS=Bos taurus GN=GJB1 PE=2 SV=1	0.0	[1..283]	[1..284]
CXB1_MACFA - Gap junction beta-1 protein OS=Macaca fascicularis GN=GJB1 PE=2 SV=1	0.0	[1..283]	[1..283]
gi\|477928 - gi\|477928\|pir\|\|B49769 gap junction protein Cx32 - mouse	0.0	[1..283]	[1..283]
CXB1_RAT - Gap junction beta-1 protein OS=Rattus norvegicus GN=Gjb1 PE=1 SV=1 CXB1_MOUSE - Gap junction beta-1 protein OS=Mus musculus GN=Gjb1 PE=1 SV=3	0.0	[1..283]	[1..283]
gi\|61367824, gi\|... - gi\|61367824\|gb\|AAX43052.1\| gap junction protein beta 1 [synthetic construct], gi\|54695526\|gb\|AAV3813...	0.0	[1..283]	[1..283]
gi\|30909101 - gi\|30909101\|gb\|AAP37453.1\| gap junction protein connexin 32 [Cricetulus griseus]	0.0	[12..283]	[1..272]

Back

Predicted Domain #1

Region A:
Residues: [1-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNWTGLYTLL SGVNRHSTAI GRVWLSVIFI FRIMVLVVAA ESVWGDEKSS FICNTLQPGC  60
   61 NSVCYDQFFP ISHVRLWSLQ LILVSTPALL VAMHVAHQQH IEKKMLRLEG HGDPLHLEEV 120
  121 KRHKVH

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	85.21467
Match:	PF00029.10
Description:	No description for PF00029.10 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [127-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISGTLWWTYV ISVVFRLLFE AVFMYVFYLL YPGYAMVRLV KCDVYPCPNT VDCFVSRPTE  60
   61 KTVFTVFMLA ASGICIILNV AEVVYLIIRA CARRAQRRSN PPSRKGSGFG HRLSPEYKQN 120
  121 EINKLLSEQD GSLKDILRRS PGTGAGLAEK SDRCSAC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits