YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: DGCR14
Organism: Homo sapiens
Length: 476 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DGCR14.

Description E-value Query
Range
Subject
Range
DGC14_MOUSE - Protein DGCR14 OS=Mus musculus GN=Dgcr14 PE=1 SV=2
651.0 [0..1] [476..1]
gi|60653733 - gi|60653733|gb|AAX29560.1| DiGeorge syndrome critical region gene 14 [synthetic construct]
650.0 [0..1] [476..1]
gi|109093256 - gi|109093256|ref|XP_001104496.1| PREDICTED: similar to DiGeorge syndrome critical region protein 14 ...
649.0 [0..1] [476..1]
gi|55661716 - gi|55661716|ref|XP_515236.1| PREDICTED: DiGeorge syndrome critical region protein 14 isoform 4 [Pan ...
646.0 [0..1] [476..1]
gi|12804313 - gi|12804313|gb|AAH03015.1|AAH03015 Similar to expressed sequence 2 embryonic lethal [Homo sapiens]
646.0 [0..2] [476..1]
gi|149019763, gi... - gi|60223077|ref|NP_001012490.1| DiGeorge syndrome critical region protein 14 [Rattus norvegicus], gi...
644.0 [0..1] [476..1]

Back

Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METPGASASS LLLPAASRPP RKREAGEAGA ATSKQRVLDE EEYIEGLQTV IQRDFFPDVE  60
   61 KLQAQKEYLE AEENGDLERM RQIAIKFGSA LGKMSREPPP PYVTPATFET PEVHAGTGVV 120
  121 GNKPRPRGRG LEDGEAGEEE EKEP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.550 a.118.8 TPR-like
View Download 0.476 c.78.2 Aspartate/glutamate racemase
View Download 0.476 c.78.2 Aspartate/glutamate racemase
View Download 0.474 a.188.1 Description not found.
View Download 0.447 a.29.12 Description not found.
View Download 0.379 a.246.2 Description not found.
View Download 0.305 a.118.8 TPR-like
View Download 0.303 c.13.2 Anti-sigma factor antagonist SpoIIaa

Predicted Domain #2
Region A:
Residues: [145-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSLDVFLSR YTSEDNASFQ EIMEVAKERS RARHAWLYQA EEEFEKRQKD NLELPSAEHQ  60
   61 AIESSQASVE TWKYKAKNSL MYYPEGVPDE EQLFKKPRQV VHKNTRFLRD PFSQALSRCQ 120
  121 LQQAAALNAQ HKQGKVGPDG KELIPQESPR VGGFGFVATP SPAPGVNESP MMTWGEVENT 180
  181 PLRVEGSETP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [335-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YVDRTPGPAF KILEPGRRER LGLKMANEAA AKNRAKKQEA LRRVTENLAS LTPKGLSPAM  60
   61 SPALQRLVSR TASKYTDRAL RASYTPSPAR STHLKTPASG LQTPTSTPAP GSATRTPLTQ 120
  121 DPASITDNLL QLPARRKASD FF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.396 a.22.1 Histone-fold
View Download 0.372 a.29.13 Description not found.
View Download 0.306 d.58.57 Description not found.
View Download 0.222 a.24.9 alpha-catenin/vinculin
View Download 0.220 a.22.1 Histone-fold
View Download 0.208 a.22.1 Histone-fold
View Download 0.201 a.45.1 Glutathione S-transferase (GST), C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle