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View Structure Prediction Details

Protein: CD59
Organism: Homo sapiens
Length: 128 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CD59.

Description E-value Query
Range		 Subject
Range
gi|60653791, gi|... - gi|60653793|gb|AAX29590.1| CD59 antigen p18-20 [synthetic construct], gi|60653791|gb|AAX29589.1| CD5...
 4.0E-54 [1..128] [1..128]
CD59_AOTTR - CD59 glycoprotein OS=Aotus trivirgatus GN=CD59 PE=3 SV=1
 1.0E-53 [1..128] [1..128]
CD59_PONAB - CD59 glycoprotein OS=Pongo abelii GN=CD59 PE=2 SV=1
CD59_PONPY - CD59 glycoprotein precursor - Pongo pygmaeus (Orangutan)
 1.0E-52 [1..128] [1..128]
CD59_SAISC - CD59 glycoprotein OS=Saimiri sciureus GN=CD59 PE=2 SV=1
 2.0E-52 [1..128] [1..131]
gi|90077478 - gi|90077478|dbj|BAE88419.1| unnamed protein product [Macaca fascicularis]
gi|109106850, gi... - gi|109106854|ref|XP_001083003.1| PREDICTED: similar to CD59 antigen p18-20 isoform 4 [Macaca mulatta...
 5.0E-52 [1..128] [1..128]
CD59_MACFA - CD59 glycoprotein OS=Macaca fascicularis GN=CD59 PE=2 SV=1
 2.0E-51 [1..128] [1..128]
ENSCJAT00000020355 - null
CD59_CALSQ - CD59 glycoprotein OS=Callithrix sp. GN=CD59 PE=3 SV=1
 5.0E-49 [1..128] [1..128]
gi|114636912 - gi|114636912|ref|XP_001140212.1| PREDICTED: similar to precursor polypeptide (AA -25 to 103) [Pan tr...
 5.0E-47 [1..103] [154..256]

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Predicted Domain #1
Region A:
Residues: [1-128] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIQGGSVLF GLLLVLAVFC HSGHSLQCYN CPNPTADCKT AVNCSSDFDA CLITKAGLQV  60
   61 YNKCWKFEHC NFNDVTTRLR ENELTYYCCK KDLCNFNEQL ENGGTSLSEK TVLLLVTPFL 120
  121 AAAWSLHP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.522879
Match: 2j8bA
Description: No description for 2j8bA was found.

Predicted functions:

Term Confidence Notes
receptor activity 2.70083456904638 bayes_pls_golite062009
U-plasminogen activator receptor activity 2.67622889349209 bayes_pls_golite062009
signal transducer activity 2.48263944107373 bayes_pls_golite062009
molecular transducer activity 2.48263944107373 bayes_pls_golite062009
binding 1.78861011884769 bayes_pls_golite062009
growth factor binding 1.43582806978958 bayes_pls_golite062009
cytokine binding 1.30600639196836 bayes_pls_golite062009
protein binding 1.22727766276611 bayes_pls_golite062009
receptor binding 1.17689017024912 bayes_pls_golite062009
transforming growth factor beta binding 0.855590728274459 bayes_pls_golite062009
receptor serine/threonine kinase binding 0.50636160522572 bayes_pls_golite062009
pattern binding 0.21003196804615 bayes_pls_golite062009
glycosaminoglycan binding 0.12571671769483 bayes_pls_golite062009
polysaccharide binding 0.0522124179603294 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle