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View Structure Prediction Details

Protein: CTDSP1
Organism: Homo sapiens
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CTDSP1.

Description E-value Query
Range
Subject
Range
gi|74005486 - gi|74005486|ref|XP_851188.1| PREDICTED: similar to CTD (carboxy-terminal domain, RNA polymerase II, ...
3.0E-87 [1..261] [1..261]
gi|109100976 - gi|109100976|ref|XP_001090300.1| PREDICTED: similar to CTD (carboxy-terminal domain, RNA polymerase ...
5.0E-87 [1..261] [1..261]
gi|114583310 - gi|114583310|ref|XP_001156881.1| PREDICTED: CTD (carboxy-terminal domain, RNA polymerase II, polypep...
6.0E-87 [1..261] [1..261]
gi|109487310, gi... - gi|62655202|ref|XP_343589.2| PREDICTED: similar to Carboxy-terminal domain RNA polymerase II polypep...
1.0E-86 [1..261] [1..261]
CTDS1_MOUSE - Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 OS=Mus musculus GN=Ctdsp...
1.0E-86 [1..261] [1..261]
gi|32813443, gi|... - gi|32813443|ref|NP_872580.1| CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small p...
2.0E-85 [1..261] [1..260]
gi|6572954 - gi|6572954|gb|AAF17482.1|AF189774_1 NLI-interacting factor isoform T2; NLI/Ldb1/CLIM interacting fac...
5.0E-84 [1..257] [1..261]
gi|76648308 - gi|76648308|ref|XP_618630.2| PREDICTED: similar to small CTD phosphatase 3 isoform 2 isoform 1 [Bos ...
6.0E-83 [1..257] [1..262]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSSAVITQI SKEEARGPLR GKGDQKSAAS QKPRSRGILH SLFCCVCRDD GEALPAHSGA  60
   61 PLLVEENGAI PK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTPVQYLLPE AKAQDSDKIC VVIDLDETLV HSSFKPVNNA DFIIPVEIDG VVHQVYVLKR  60
   61 PHVDEFLQRM GELFECVLFT ASLAKYADPV ADLLDKWGAF RARLFRESCV FHRGNYVKDL 120
  121 SRLGRDLRRV LILDNSPASY VFHPDNAVPV ASWFDNMSDT ELHDLLPFFE QLSRVDDVYS 180
  181 VLRQPRPGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.69897
Match: 1ta0A
Description: Three-dimensional structure of a RNA-polymerase II binding protein with associated ligand.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.877696725573375 bayes_pls_golite062009
catalytic activity 0.786540433906087 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle