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View Structure Prediction Details

Protein: RBM4B
Organism: Homo sapiens
Length: 359 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBM4B.

Description E-value Query
Range		 Subject
Range
gi|57099639, gi|... - gi|73982909|ref|XP_852248.1| PREDICTED: similar to zinc responsive protein ZD7 isoform 2 [Canis fami...
 9.0E-56 [1..359] [1..359]
RBM4_RABIT - RNA-binding protein 4 OS=Oryctolagus cuniculus GN=RBM4 PE=2 SV=1
 1.0E-55 [1..359] [1..359]
gi|86438058, gi|... - gi|86438058|gb|AAI12498.1| RNA binding motif protein 4B [Bos taurus], gi|76658008|ref|XP_582093.2| P...
 3.0E-55 [1..359] [1..359]
RBM4B_PIG - RNA-binding protein 4B OS=Sus scrofa GN=RBM4B PE=2 SV=1
 8.0E-55 [1..359] [1..359]
gi|109459737 - gi|109459737|ref|XP_215201.4| PREDICTED: similar to RNA-binding protein 4 (RNA-binding motif protein...
 9.0E-55 [1..359] [117..481]
RBM4_MOUSE - RNA-binding protein 4 OS=Mus musculus GN=Rbm4 PE=1 SV=1
 2.0E-54 [1..359] [1..361]
RBM4 - RNA binding motif protein 4
RBM4_MACFA - RNA-binding protein 4 OS=Macaca fascicularis GN=RBM4 PE=2 SV=1
ENSMMUT000000445... - null, null, null, null
gi|167774193 - gi|167774193|gb|ABZ92531.1| RNA binding motif protein 4 [synthetic construct]
ENSPTRT00000007346 - null
 3.0E-53 [1..359] [1..364]

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Predicted Domain #1
Region A:
Residues: [1-74] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKLFIGNLP REATEQEIRS LFEQYGKVLE CDIIKNYGFV HIEDKTAAED AIRNLHHYKL  60
   61 HGVNINVEAS KNKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.0
Match: 2dnqA
Description: No description for 2dnqA was found.

Predicted Domain #2
Region A:
Residues: [75-164] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KASTKLHVGN ISPTCTNQEL RAKFEEYGPV IECDIVKDYA FVHMERAEDA VEAIRGLDNT  60
   61 EFQGKRMHVQ LSTSRLRTAP GMGDQSGCYR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2dgtA
Description: No description for 2dgtA was found.

Predicted Domain #3
Region A:
Residues: [165-266] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CGKEGHWSKE CPVDRTGRVA DFTEQYNEQY GAVRTPYTMG YGESMYYNDA YGALDYYKRY  60
   61 RVRSYEAVAA AAAASAYNYA EQTMSHLPQV QSTTVTSHLN ST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.30103
Match: 2bz2A
Description: No description for 2bz2A was found.

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [267-359] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVDPYDRHLL PNSGAAATSA AMAAAAATTS SYYGRDRSPL RRAAAMLPTV GEGYGYGPES  60
   61 ELSQASAATR NSLYDMARYE REQYVDRARY SAF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.556 a.39.1 EF-hand
View Download 0.481 a.156.1 S13-like H2TH domain
View Download 0.431 a.3.1 Cytochrome c
View Download 0.491 a.77.1 DEATH domain
View Download 0.498 d.16.1 FAD-linked reductases, C-terminal domain

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle