YRC Public Data Repository - Protein Structure Prediction

Protein:	NDEL1
Organism:	Homo sapiens
Length:	345 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NDEL1.

Description	E-value	Query Range	Subject Range
gi\|68388302 - gi\|68388302\|ref\|XP_696268.1\| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]	5.0E-27	[4..297]	[2114..2393]
gi\|114669127 - gi\|114669127\|ref\|XP_001166739.1\| PREDICTED: hypothetical protein isoform 4 [Pan troglodytes]	2.0E-26	[1..345]	[66..410]
gi\|73955651 - gi\|73955651\|ref\|XP_850046.1\| PREDICTED: similar to nudE nuclear distribution gene E homolog like 1 (...	4.0E-26	[1..345]	[65..409]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1	3.0E-24	[4..297]	[1112..1397]
gi\|76643949 - gi\|76643949\|ref\|XP_882447.1\| PREDICTED: similar to myosin, heavy polypeptide 8, skeletal muscle, per...	1.0E-23	[10..297]	[1069..1348]
gi\|225000798 - gi\|225000798\|gb\|AAI72386.1\| Myosin, heavy chain 8, skeletal muscle, perinatal [synthetic construct] MYH8 - myosin, heavy chain 8, skeletal muscle, perinatal	1.0E-23	[4..297]	[1113..1398]

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Predicted Domain #1

Region A:
Residues: [1-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGEDIPDFS SLKEETAYWK ELSLKYKQSF QEARDELVEF QEGSRELEAE LEAQLVQAEQ  60
   61 RNRDLQADNQ RLKYEVEALK EKLEHQYAQS YKQVSVLEDD LSQTRAIKEQ LHKYVRELEQ 120
  121 ANDDLERAKR ATIVSLEDFE QRLNQAIERN AFLESELDEK ESLLVSVQRL KDEARDLRQE 180
  181 LAVRERQQEV TRKSAPSSPT LDCEKMDSAV QASLSLPATP VGKGTENTFP SPKAIPNGFG 240
  241 TSPLTPSARI SALNIVGDLL RKVGALESKL AACRNFAKDQ ASRKSYISGN VNCGVLNGNG 300
  301 TKFSRSGHTS FFDKGAVNGF DPAPPPPGLG SSRPSSAPGM LPLSV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.0
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits