YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|119619265, gi...
Organism:	Homo sapiens
Length:	452 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119619265, gi....

Description	E-value	Query Range	Subject Range
GLRA2 - glycine receptor, alpha 2	0.0	[1..452]	[1..452]
gi\|109129969 - gi\|109129969\|ref\|XP_001099462.1\| PREDICTED: glycine receptor, alpha 2 isoform 3 [Macaca mulatta] gi\|114687826 - gi\|114687826\|ref\|XP_001137046.1\| PREDICTED: glycine receptor, alpha 2 isoform 7 [Pan troglodytes] gi\|74006497 - gi\|74006497\|ref\|XP_857203.1\| PREDICTED: similar to Glycine receptor alpha-2 chain precursor isoform ...	0.0	[1..452]	[1..452]
gi\|6980952, gi\|2... - pir\|\|S14816 glycine receptor alpha-2 chain variant A precursor - rat, gi\|6980952\|ref\|NP_036700.1\| g...	0.0	[1..452]	[1..452]
GLRA2_MOUSE - Glycine receptor subunit alpha-2 OS=Mus musculus GN=Glra2 PE=1 SV=1	0.0	[1..452]	[1..452]
gi\|114687832 - gi\|114687832\|ref\|XP_001136903.1\| PREDICTED: glycine receptor, alpha 2 isoform 6 [Pan troglodytes]	0.0	[1..452]	[1..459]
gi\|109129973 - gi\|109129973\|ref\|XP_001099263.1\| PREDICTED: glycine receptor, alpha 2 isoform 1 [Macaca mulatta]	0.0	[1..452]	[1..464]

Back

Predicted Domain #1

Region A:
Residues: [1-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRQLVNILT ALFAFFLETN HFRTAFCKDH DSRSGKQPSQ TLSPSDFLDK LMGRTSGYDA  60
   61 RIRPNFKGPP VNVTCNIFIN SFGSIAETTM DYRVNIFLRQ QWNDSRLAYS EYPDDSLDLD 120
  121 PSMLDSIWKP DLFFANEKGA NFHDVTTDNK LLRISKNGKV LYSIRLTLTL SCPMDLKNFP 180
  181 MDVQTCTMQL ESFGYTMNDL IFEWLSDGPV QVAEGLTLPQ FILKEEKELG YCTKHYNTGK 240
  241 FTCIEVKFHL ERQMGYYLIQ MYIPSLLIVI LSWVSFWINM DAAPARVALG ITTVLTMTTQ 300
  301 SSGSRASLPK VSYVKAIDIW MAVCLLFVFA ALLEYAAVNF VSRQHKEFLR LRRRQKRQNK 360
  361

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.69897
Match:	2bg9A
Description:	Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [361-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDVTRESRF NFSGYGMGHC LQVKDGTAVK ATPANPLPQP PKDGDAIKKK FVDRAKRIDT  60
   61 ISRAAFPLAF LIFNIFYWIT YKIIRHEDVH KK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.69897
Match:	1oedC
Description:	Acetylcholine receptor protein, delta chain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits