YRC Public Data Repository - Protein Structure Prediction

Protein:	CDK1
Organism:	Homo sapiens
Length:	297 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDK1.

Description	E-value	Query Range	Subject Range
gi\|51247099, gi\|... - gi\|51247109\|pdb\|1OIY\|C Chain C, Structure Of Human Thr160-Phospho Cdk2CYCLIN A COMPLEXED With A 6-Cy...	313.0	[0..1]	[297..5]
gi\|109097199 - gi\|109097199\|ref\|XP_001113345.1\| PREDICTED: cyclin-dependent kinase 2 isoform 6 [Macaca mulatta]	312.0	[0..1]	[297..1]
CDK2_RAT - Cyclin-dependent kinase 2 OS=Rattus norvegicus GN=Cdk2 PE=1 SV=1 gi\|710025 - gi\|710025\|dbj\|BAA05947.1\| cyclin dependent kinase 2-alpha [Rattus rattus]	312.0	[0..1]	[297..1]
gi\|147905993, gi... - gi\|47682830\|gb\|AAH70640.1\| MGC81499 protein [Xenopus laevis], gi\|147905993\|ref\|NP_001084976.1\| hypot...	312.0	[0..1]	[297..1]
gi\|117499872 - gi\|117499872\|gb\|ABK34941.1\| cyclin-dependent kinase 2 [Capra hircus] gi\|215983068, gi... - gi\|215983068\|ref\|NP_001135981.1\| cyclin-dependent kinase 2 [Ovis aries], gi\|213688920\|gb\|ACJ53943.1\|... CDK2_BOVIN - Cyclin-dependent kinase 2 OS=Bos taurus GN=CDK2 PE=2 SV=1	312.0	[0..1]	[297..1]
tr\|M3WJU6\|M3WJU6... - Cyclin dependent kinase 2 OS=Felis catus GN=CDK2 PE=3 SV=1 gi\|73968309 - gi\|73968309\|ref\|XP_856049.1\| PREDICTED: similar to cyclin-dependent kinase 2 isoform 6 [Canis famili...	312.0	[0..1]	[297..1]

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Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDYTKIEKI GEGTYGVVYK GRHKTTGQVV AMKKIRLESE EEGVPSTAIR EISLLKELRH  60
   61 PNIVSLQDVL MQDSRLYLIF EFLSMDLKKY LDSIPPGQYM DSSLVKSYLY QILQGIVFCH 120
  121 SRRVLHRDLK PQNLLIDDKG TIKLADFGLA RAFGIPIRVY THEVVTLWYR SPEVLLGSAR 180
  181 YSTPVDIWSI GTIFAELATK KPLFHGDSEI DQLFRIFRAL GTPNNEVWPE VESLQDYKNT 240
  241 FPKWKPGSLA SHVKNLDENG LDLLSKMLIY DPAKRISGKM ALNHPYFNDL DNQIKKM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.522879
Match:	2iw8A
Description:	No description for 2iw8A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits