YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|4758496, gi\|3...
Organism:	Homo sapiens
Length:	371 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4758496, gi|3....

Description	E-value	Query Range	Subject Range
gi\|87578157, gi\|... - gi\|87578157\|gb\|AAI13288.1\| H2A histone family, member Y [Bos taurus], gi\|114052404\|ref\|NP_001039805....	0.0	[1..371]	[1..371]
H2AY_RAT - Core histone macro-H2A.1 OS=Rattus norvegicus GN=H2afy PE=1 SV=4	0.0	[1..371]	[1..371]
gi\|73971330 - gi\|73971330\|ref\|XP_538635.2\| PREDICTED: similar to H2A histone family, member Y isoform 3 [Canis fam...	0.0	[1..371]	[41..412]
tr\|M3WJR3\|M3WJR3... - Core histone macro-H2A OS=Felis catus GN=H2AFY PE=4 SV=1 H2AFY - H2A histone family, member Y gi\|114601775, gi... - gi\|114601779\|ref\|XP_001168554.1\| PREDICTED: similar to H2AFY protein isoform 8 [Pan troglodytes], gi... gi\|109078673, gi... - gi\|109078675\|ref\|XP_001110589.1\| PREDICTED: H2A histone family, member Y isoform 4 [Macaca mulatta],...	0.0	[1..371]	[1..372]
gi\|114601789 - gi\|114601789\|ref\|XP_001168507.1\| PREDICTED: similar to H2AFY protein isoform 6 [Pan troglodytes]	0.0	[1..371]	[1..380]
gi\|94396067 - gi\|94396067\|ref\|XP_990122.1\| PREDICTED: similar to H2A histone family, member Y isoform 4 [Mus muscu...	0.0	[1..371]	[1..381]

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Predicted Domain #1

Region A:
Residues: [1-128]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRGGKKKS TKTSRSAKAG VIFPVGRMLR YIKKGHPKYR IGVGAPVYMA AVLEYLTAEI  60
   61 LELAGNAARD NKKGRVTPRH ILLAVANDEE LNQLLKGVTI ASGGVLPNIH PELLAKKRGS 120
  121 KGKLEAII

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.0
Match:	1u35C
Description:	Crystal structure of the nucleosome core particle containing the histone domain of macroH2A
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [129-371]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPPPAKKAKS PSQKKPVSKK AGGKKGARKS KKQGEVSKAA SADSTTEGTP ADGFTVLSTK  60
   61 SLFLGQKLNL IHSEISNLAG FEVEAIINPT NADIDLKDDL GNTLEKKGGK EFVEAVLELR 120
  121 KKNGPLEVAG AAVSAGHGLP AKFVIHCNSP VWGADKCEEL LEKTVKNCLA LADDKKLKSI 180
  181 AFPSIGSGRN GFPKQTAAQL ILKAISSYFV STMSSSIKTV YFVLFDSESI GIYVQEMAKL 240
  241 DAN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.522879
Match:	1zr5A
Description:	Crystal structure of the macro-domain of human core histone variant macroH2A1.2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits