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View Structure Prediction Details

Protein: TMOD3
Organism: Homo sapiens
Length: 352 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TMOD3.

Description E-value Query
Range
Subject
Range
gi|57108515 - gi|57108515|ref|XP_544679.1| PREDICTED: similar to Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)...
192.0 [0..1] [352..1]
gi|109081145 - gi|109081145|ref|XP_001084796.1| PREDICTED: tropomodulin 3 (ubiquitous) isoform 4 [Macaca mulatta]
191.0 [0..1] [352..1]
gi|57997483 - gi|57997483|emb|CAI46036.1| hypothetical protein [Homo sapiens]
188.0 [0..1] [352..1]
gi|114657088 - gi|114657088|ref|XP_523077.2| PREDICTED: tropomodulin 3 (ubiquitous) isoform 2 [Pan troglodytes]
188.0 [0..1] [352..1]
gi|7288863, gi|4... - gi|7288863|gb|AAF45300.1|AF237632_1 ubiquitous tropomodulin U-Tmod [Sus scrofa], gi|47523650|ref|NP_...
188.0 [0..1] [352..1]
gi|53127965, gi|... - gi|94536823|ref|NP_001005813.1| tropomodulin 3 [Gallus gallus], gi|53127965|emb|CAG31260.1| hypothet...
185.0 [0..1] [343..1]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALPFRKDLE KYKDLDEDEL LGNLSETELK QLETVLDDLD PENALLPAGF RQKNQTSKST  60
   61 TGPFDREHLL SYLEKEALEH KDREDYVPYT GEKKGK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.350 a.118.11 Cytochrome c oxidase subunit E
View Download 0.347 d.240.1 Description not found.
View Download 0.332 a.133.1 Phospholipase A2, PLA2
View Download 0.323 a.133.1 Phospholipase A2, PLA2
View Download 0.302 c.52.1 Restriction endonuclease-like
View Download 0.291 a.118.11 Cytochrome c oxidase subunit E
View Download 0.260 a.11.2 Second domain of FERM
View Download 0.259 a.11.2 Second domain of FERM
View Download 0.234 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.229 a.57.1 Protein HNS-dependent expression A; HdeA

Predicted Domain #2
Region A:
Residues: [97-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFIPKQKPVQ TFTEEKVSLD PELEEALTSA SDTELCDLAA ILGMHNLITN TKFCNIMGSS  60
   61 NGVDQEHFSN VVKGEKILPV FDEPPNPT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.154902
Match: 2v9sA
Description: No description for 2v9sA was found.

Predicted Domain #3
Region A:
Residues: [185-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVEESLKRTK ENDAHLVEVN LNNIKNIPIP TLKDFAKALE TNTHVKCFSL AATRSNDPVA  60
   61 TAFAEMLKVN KTLKSLNVES NFITGVGILA LIDALRDNET LAELKIDNQR QQLGTAVELE 120
  121 MAKMLEENTN ILKFGYQFTQ QGPRTRAANA ITKNNDLVRK RRVEGDHQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.09691
Match: 1pgvA
Description: Tropomodulin C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle