YRC Public Data Repository - Protein Structure Prediction

Protein:	SLC5A4
Organism:	Homo sapiens
Length:	659 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLC5A4.

Description	E-value	Query Range	Subject Range
gi\|114686054 - gi\|114686054\|ref\|XP_525573.2\| PREDICTED: solute carrier family 5 (low affinity glucose cotransporter...	0.0	[1..659]	[1..659]
gi\|346476 - pir\|\|A44432 amino acid transport protein - pig SC5A4_PIG - Low affinity sodium-glucose cotransporter OS=Sus scrofa GN=SLC5A4 PE=2 SV=1	0.0	[1..659]	[1..660]
gi\|109093971 - gi\|109093971\|ref\|XP_001112250.1\| PREDICTED: similar to solute carrier family 5 (low affinity glucose...	0.0	[1..659]	[1..659]
gi\|126352558, gi... - gi\|13539197\|emb\|CAC35538.1\| Na+/glucose co-transporter [Equus caballus], gi\|126352558\|ref\|NP_0010753...	0.0	[2..659]	[3..662]
gi\|13277957, gi\|... - gi\|6563312\|gb\|AAF17249.1\|AF208031_1 SGLT1 protein [Mus musculus], gi\|13277957\|gb\|AAH03845.1\| Solute ...	0.0	[2..659]	[3..665]
gi\|1816433 - gi\|1816433\|dbj\|BAA19172.1\| Na/glucose cotransporter [Rattus norvegicus]	0.0	[2..659]	[3..665]

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Predicted Domain #1

Region A:
Residues: [1-510]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTVSPSTI AETPEPPPLS DHIRNAADIS VIVIYFLVVM AVGLWAMLKT NRGTIGGFFL  60
   61 AGRDMAWWPM GASLFASNIG SNHYVGLAGT GAASGVATVT FEWTSSVMLL ILGWIFVPIY 120
  121 IKSGVMTMPE YLKKRFGGER LQVYLSILSL FICVVLLISA DIFAGAIFIK LALGLDLYLA 180
  181 IFILLAMTAV YTTTGGLASV IYTDTLQTII MLIGSFILMG FAFNEVGGYE SFTEKYVNAT 240
  241 PSVVEGDNLT ISASCYTPRA DSFHIFRDAV TGDIPWPGII FGMPITALWY WCTNQVIVQR 300
  301 CLCGKDMSHV KAACIMCAYL KLLPMFLMVM PGMISRILYT DMVACVVPSE CVKHCGVDVG 360
  361 CTNYAYPTMV LELMPQGLRG LMLSVMLASL MSSLTSIFNS ASTLFTIDLY TKMRKQASEK 420
  421 ELLIAGRIFV LLLTVVSIVW VPLVQVSQNG QLIHYTESIS SYLGPPIAAV FVLAIFCKRV 480
  481 NEQGAFWGLM VGLAMGLIRM ITEFAYGTGS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.01
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [511-659]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLAPSNCPKI ICGVHYLYFS IVLFFGSMLV TLGISLLTKP IPDVHLYRLC WVLRNSTEER  60
   61 IDIDAEEKSQ EETDDGVEED YPEKSRGCLK KAYDLFCGLQ KGPKLTKEEE EALSKKLTDT 120
  121 SERPSWRTIV NINAILLLAV VVFIHGYYA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.03
Match:	2h8nA
Description:	No description for 2h8nA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits