YRC Public Data Repository - Protein Structure Prediction

Protein:	PGPEP1
Organism:	Homo sapiens
Length:	209 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGPEP1.

Description	E-value	Query Range	Subject Range
CCDS12375.1_1 - null gi\|109123963 - gi\|109123963\|ref\|XP_001115337.1\| PREDICTED: pyroglutamyl-peptidase I [Macaca mulatta]	2.0E-69	[1..209]	[1..209]
gi\|158341676, gi... - gi\|76620742\|ref\|XP_871502.1\| PREDICTED: hypothetical protein isoform 1 [Bos taurus], gi\|158341676\|re...	8.0E-69	[1..209]	[1..209]
PGPI_MOUSE - Pyroglutamyl-peptidase 1 OS=Mus musculus GN=Pgpep1 PE=1 SV=1	2.0E-68	[1..208]	[1..208]
PGPI_RAT - Pyroglutamyl-peptidase 1 OS=Rattus norvegicus GN=Pgpep1 PE=1 SV=1	3.0E-68	[1..208]	[1..208]
PCP_STRP1 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M1 GN=pcp PE=3 SV=1 PCP_STRPZ - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M49 (strain NZ131) GN=pcp PE=3 ... PCP_STRPM - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M28 GN=pcp PE=3 SV=1 PCP_STRPY - (Q01328) Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl-pepti... PCP_STRP6 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS1... gi\|15674611, gi\|... - gi\|15674611\|ref\|NP_268785.1\| pyrrolidone-carboxylate peptidase [Streptococcus pyogenes M1 GAS], gi\|1... PCP_STRPD - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M2 (strain MGAS10270) GN=pcp PE... PCP_STRP6 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M6 GN=pcp PE=1 SV=1 gi\|71853012, gi\|... - gi\|71910230\|ref\|YP_281780.1\| pyrrolidone-carboxylate peptidase [Streptococcus pyogenes MGAS5005], gi... PCP_STRPM - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M28 (strain MGAS6180) GN=pcp PE... gi\|56808173 - gi\|56808173\|ref\|ZP_00365954.1\| COG2039: Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl p... PCP_STRPG - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M5 (strain Manfredo) GN=pcp PE=...	5.0E-64	[7..209]	[2..215]
PCP_STRPF - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M4 (strain MGAS10750) GN=pcp PE... PCP_STRP8 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M18 (strain MGAS8232) GN=pcp PE... PCP_STRP8 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M18 GN=pcp PE=3 SV=1	5.0E-64	[7..209]	[2..215]
gi\|221231641, gi... - gi\|221231641\|ref\|YP_002510793.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae ATCC 70... gi\|225856527, gi... - gi\|225856527\|ref\|YP_002738038.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae P1031], gi\|22572... PCP1_STRPN - Pyrrolidone-carboxylate peptidase 1 OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TI... gi\|225728134, gi... - gi\|225861246\|ref\|YP_002742755.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae Taiwan19F-14], g... gi\|225854366, gi... - gi\|225854366\|ref\|YP_002735878.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae JJA], gi\|2257239... gi\|168493014, gi... - gi\|183577052\|gb\|EDT97580.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae CDC3059-06], gi\|16849... PCP_STRP2 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) GN... gi\|168575516, gi... - gi\|183578623\|gb\|EDT99151.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae MLV-016], gi\|16857551... PCP_STRPI - Pyrrolidone-carboxylate peptidase OS=Streptococcus pneumoniae (strain Hungary19A-6) GN=pcp PE=3 SV=1 gi\|237822246 - gi\|237822246\|ref\|ZP_04598091.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae CCRI 197... gi\|182629108, gi... - gi\|182683774\|ref\|YP_001835521.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae CGSP14]... gi\|242245140, gi... - gi\|242245140\|ref\|ZP_04799577.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae TCH8431/... gi\|148993672, gi... - gi\|148993672\|ref\|ZP_01823119.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae SP9-BS68... gi\|172042083, gi... - gi\|172042083\|gb\|EDT50129.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae CDC1873-00], gi\|16848... gi\|147925960, gi... - gi\|148988279\|ref\|ZP_01819726.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae SP6-BS73... gi\|168485808, gi... - gi\|183571051\|gb\|EDT91579.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae CDC1087-00], gi\|16848... gi\|147922981, gi... - gi\|148984590\|ref\|ZP_01817858.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae SP3-BS71... gi\|183571351, gi... - gi\|183571351\|gb\|EDT91879.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae SP195], gi\|168490293\|... gi\|183574584, gi... - gi\|183574584\|gb\|EDT95112.1\| pyroglutamyl-peptidase I [Streptococcus pneumoniae CDC0288-04], gi\|16849... PCP1_STRR6 - Pyrrolidone-carboxylate peptidase 1 OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=pcp1 P... PCP1_STRPN - Pyrrolidone-carboxylate peptidase 1 OS=Streptococcus pneumoniae GN=pcp1 PE=3 SV=1 gi\|147764991, gi... - gi\|149010510\|ref\|ZP_01831881.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae SP19-BS7... gi\|149007196, gi... - gi\|149007196\|ref\|ZP_01830860.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae SP18-BS7... gi\|147756764, gi... - gi\|148997064\|ref\|ZP_01824718.1\| pyrrolidone-carboxylate peptidase [Streptococcus pneumoniae SP11-BS7...	6.0E-64	[7..209]	[2..214]
PCP_STRPC - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M12 (strain MGAS9429) GN=pcp PE... PCP_STRPB - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M12 (strain MGAS2096) GN=pcp PE...	7.0E-64	[7..209]	[2..215]
PCP_STRP3 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M3 GN=pcp PE=3 SV=1 PCP_STRP3 - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS3... PCP_STRPQ - Pyrrolidone-carboxylate peptidase OS=Streptococcus pyogenes serotype M3 (strain SSI-1) GN=pcp PE=3 S...	1.0E-63	[7..209]	[2..215]
gi\|73986137 - gi\|73986137\|ref\|XP_541939.2\| PREDICTED: similar to Pyroglutamyl-peptidase I (Pyrrolidone-carboxylate...	5.0E-63	[12..209]	[12..209]

Back

Predicted Domain #1

Region A:
Residues: [1-209]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQPRKAVVV TGFGPFGEHT VNASWIAVQE LEKLGLGDSV DLHVYEIPVE YQTVQRLIPA  60
   61 LWEKHSPQLV VHVGVSGMAT TVTLEKCGHN KGYKGLDNCR FCPGSQCCVE DGPESIDSII 120
  121 DMDAVCKRVT TLGLDVSVTI SQDAGRYLCD FTYYTSLYQS HGRSAFVHVP PLGKPYNADQ 180
  181 LGRALRAIIE EMLDLLEQSE GKINYCHKH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.522879
Match:	1augA
Description:	Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits