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View Structure Prediction Details

Protein: ESF1
Organism: Homo sapiens
Length: 851 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESF1.

Description E-value Query
Range
Subject
Range
ESF1_MOUSE - ESF1 homolog OS=Mus musculus GN=Esf1 PE=1 SV=1
351.0 [0..1] [851..1]
gi|109092936, gi... - gi|109092938|ref|XP_001083582.1| PREDICTED: similar to ABT1-associated protein isoform 2 [Macaca mul...
334.0 [0..1] [851..1]
gi|42491219 - gi|42491219|dbj|BAD10946.1| ABTAP [Rattus rattus]
ESF1_RAT - ESF1 homolog OS=Rattus norvegicus GN=Esf1 PE=1 SV=1
327.0 [0..1] [851..1]
gi|73991143 - gi|73991143|ref|XP_534341.2| PREDICTED: similar to ABT1-associated protein isoform 1 [Canis familiar...
313.0 [0..1] [851..1]
gi|71895765, gi|... - gi|71895765|ref|NP_001026690.1| ESF1, nucleolar pre-rRNA processing protein, homolog [Gallus gallus]...
260.0 [0..1] [851..1]
gi|28374250, gi|... - gi|28374250|gb|AAH46107.1| ESF1 protein [Homo sapiens], gi|116283795|gb|AAH30513.1| ESF1 protein [Ho...
258.0 [0..1] [595..1]
gi|9916, gi|627059 - gi|9916|emb|CAA39663.1| liver stage antigen [Plasmodium falciparum], pir||A45592 liver stage antigen...
257.0 [0..4] [848..642]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKQEIMSD QRFRRVAKDP RFWEMPEKDR KVKIDKRFRA MFHDKKFKLN YAVDKRGRPI  60
   61 SHSTTEDLKR FYDLSDSDSN LS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.402 N/A N/A a.230.1 Description not found.
View Download 0.367 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.367 N/A N/A a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.366 N/A N/A a.77.1 DEATH domain
View Download 0.366 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.362 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.320 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.316 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.310 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.252 N/A N/A c.114.1 YchN-like

Predicted Domain #2
Region A:
Residues: [83-194]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEDSKALSQK KIKKKKTQTK KEIDSKNLVE KKKETKKANH KGSENKTDLD NSIGIKKMKT  60
   61 SCKFKIDSNI SPKKDSKEFT QKNKKEKKNI VQHTTDSSLE EKQRTLDSGT SE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [195-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVKSPRIECS KTRREMQSVV QLIMTRDSDG YENSTDGEMC DKDALEEDSE SVSEIGSDEE  60
   61 SENEITSVGR ASGDDDGSED DEEEDEDEEE DEDEDSEDDD KSDSGPDLAR GKGNIETSSE 120
  121 DEDDTADLFP EESGFEHAWR ELDKDAPRAD E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [346-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITRRLAVCNM DWDRLKAKDL LALFNSFKPK GGVIFSVKIY PSEFGKERMK EEQVQGPVEL  60
   61 LSIPEDAPEK DWTSREKLRD YQFKRLKYYY AVVDCDSPET ASKIYED

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.567 c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.567 c.26.2 Adenine nucleotide alpha hydrolases-like
View Download 0.492 d.58.5 GlnB-like
View Download 0.486 d.110.4 SNARE-like
View Download 0.486 d.110.4 SNARE-like
View Download 0.481 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.481 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.478 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.478 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.462 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.335 d.58.4 Dimeric alpha+beta barrel
View Download 0.319 d.80.1 Tautomerase/MIF
View Download 0.295 c.98.2 HPr kinase/phoshatase HprK N-terminal domain

Predicted Domain #5
Region A:
Residues: [453-694]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CDGLEFESSC SFIDLRFIPD DITFDDEPKD VASEVNLTAY KPKYFTSAAM GTSTVEITWD  60
   61 ETDHERITML NRKFKKEELL DMDFQAYLAS SSEDEEEIEE ELQGDDGVNV EEDGKTKKSQ 120
  121 KDDEEQIAKY RQLLQVIQEK EKKGKENDME MEIKWVPGLK ESAEEMVKNK LEGKDKLTPW 180
  181 EQFLEKKKEK KRLKRKQKAL AEEASEEELP SDVDLNDPYF AEEVKQIGIN KKSVKSAKDG 240
  241 TS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [695-851]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEEEIEIERQ KAEMALLMMD EDEDSKKHFN YNKIVEHQNL SKKKKKQLMK KKELIEDDFE  60
   61 VNVNDARFQA MYTSHLFNLD PSDPNFKKTK AMEKILEEKA RQRERKEQEL TQAIKKKESE 120
  121 IEKESQRKSI DPALSMLIKS IKTKTEQFQA RKKQKVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle