YRC Public Data Repository - Protein Structure Prediction

Protein:	TUBB1
Organism:	Homo sapiens
Length:	451 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TUBB1.

Description	E-value	Query Range	Subject Range
gi\|48095525 - gi\|48095525\|ref\|XP_392313.1\| PREDICTED: similar to -Tubulin at 56D CG9277-PB, isoform B [Apis mellif...	0.0	[1..446]	[1..446]
gi\|91086093 - gi\|91086093\|ref\|XP_967267.1\| PREDICTED: similar to beta1-tubulin [Tribolium castaneum]	0.0	[1..446]	[1..446]
gi\|157132376, gi... - gi\|157132376\|ref\|XP_001656025.1\| tubulin beta chain [Aedes aegypti], gi\|108881720\|gb\|EAT45945.1\| tub...	0.0	[1..446]	[1..446]
gi\|74223737 - gi\|74223737\|dbj\|BAE28709.1\| unnamed protein product [Mus musculus]	0.0	[1..429]	[1..429]
TBB1_MAIZE - Tubulin beta-1 chain OS=Zea mays GN=TUBB1 PE=2 SV=1	0.0	[1..430]	[1..430]
gi\|22297093 - gi\|22297093\|gb\|AAM95344.1\|AF487838_1 beta-tubulin Cyca-1b [Cyathostomum catinatum]	0.0	[1..448]	[1..448]
gi\|157767470 - gi\|157767470\|ref\|XP_001667215.1\| Hypothetical protein CBG16137 [Caenorhabditis briggsae AF16] tbb-4 - tubulin beta chain status:Partially_confirmed UniProt:P41937 protein_id:CAA86310.1 gi\|39596183, gi\|... - gi\|39596183\|emb\|CAE69820.1\| Hypothetical protein CBG16137 [Caenorhabditis briggsae], gi\|187026681\|em...	0.0	[1..442]	[1..442]
gi\|73996516 - gi\|73996516\|ref\|XP_850665.1\| PREDICTED: similar to Tubulin alpha-2 chain (Alpha-tubulin 2) isoform 2...	0.0	[1..439]	[1..449]

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Predicted Domain #1

Region A:
Residues: [1-451]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIVHIQIG QCGNQIGAKF WEMIGEEHGI DLAGSDRGAS ALQLERISVY YNEAYGRKYV  60
   61 PRAVLVDLEP GTMDSIRSSK LGALFQPDSF VHGNSGAGNN WAKGHYTEGA ELIENVLEVV 120
  121 RHESESCDCL QGFQIVHSLG GGTGSGMGTL LMNKIREEYP DRIMNSFSVM PSPKVSDTVV 180
  181 EPYNAVLSIH QLIENADACF CIDNEALYDI CFRTLKLTTP TYGDLNHLVS LTMSGITTSL 240
  241 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTAQGSQQ YRALSVAELT QQMFDARNTM 300
  301 AACDLRRGRY LTVACIFRGK MSTKEVDQQL LSVQTRNSSC FVEWIPNNVK VAVCDIPPRG 360
  361 LSMAATFIGN NTAIQEIFNR VSEHFSAMFK RKAFVHWYTS EGMDINEFGE AENNIHDLVS 420
  421 EYQQFQDAKA VLEEDEEVTE EAEMEPEDKG H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1ffxB
Description:	Tubulin:stathmin-like domain complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits