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View Structure Prediction Details

Protein: gi|14110387, gi|...
Organism: Homo sapiens
Length: 1512 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|14110387, gi|....

Description E-value Query
Range
Subject
Range
gi|114613058 - gi|114613058|ref|XP_001139939.1| PREDICTED: cell division cycle 2-like 5 isoform 4 [Pan troglodytes]
702.0 [0..1] [1512..1]
CDK13 - cyclin-dependent kinase 13
gi|195934749 - gi|195934749|gb|AAI68380.1| Cell division cycle 2-like 5 (cholinesterase-related cell division contr...
699.0 [0..1] [1512..1]
CDK13_MOUSE - Cyclin-dependent kinase 13 OS=Mus musculus GN=Cdk13 PE=1 SV=3
661.0 [0..1] [1512..1]
gi|109505848 - gi|109505848|ref|XP_001053539.1| PREDICTED: similar to Cell division cycle 2-like protein kinase 5 (...
653.0 [0..1] [1512..1]
gi|73981899 - gi|73981899|ref|XP_533082.2| PREDICTED: similar to Cell division cycle 2-like protein kinase 5 (CDC2...
625.0 [0..403] [1512..269]
gi|50732998 - gi|50732998|ref|XP_418864.1| PREDICTED: similar to cell division cycle 2-like 5 isoform 1; CDC2-rela...
546.0 [0..150] [1512..187]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSSSDTALG GGGGLSWAEK RLEERRKRRR FLSPQQPPLL LPLLQPQLLQ PPPPPPPLLF  60
   61 LAAPGTAAAA AAAAAASSSC FSPGPPLEVK RLARGKRRAG GRQKRRRGPR AGQEAEKRRV 120
  121 FSLPQPQQDG GGGASSGGGV TPLVEYEDVS SQSEQGLLLG GASAATAATA AGGTGGSGGS 180
  181 PASSSGTQRR GEGSERRPRR DRR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [204-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSGRSKERH REHRRRDGQR GGSEASKSRS RHSHSGEERA EVAKSGSSSS SGGRRKSASA  60
   61 TSSSSSSRKD RDSKAHRSRT KSSKEPPSAY KEPPKAYRED KTEPKAYRRR RSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [317-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPLGGRDDSP VSHRASQSLR SRKSPSPAGG GSSPYSRRLP RSPSPYSRRR SPSYSRHSSY  60
   61 ERGGDVSPSP YSSSSWRRSR SPYSPVLRRS GKSRSRSPYS SRHSRSRSRH RLSRSRSRHS 120
  121 SISPSTLTLK SSLAAELNKN KKARAAEAAR AAEAAKAAEA TKAAEAAAKA AKASNTSTPT 180
  181 KGNTETSASA SQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [509-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNHVKDVKKI KIEHAPSPSS GGTLKNDKAK TKPPLQVTKV ENNLIVDKAT KKAVIVGKES  60
   61 KSAATKEESV SLKEKTKPLT PSIGAKEKEQ HVALVTSTLP PLPLPPMLPE DKEADSLRGN 120
  121 ISVKAVKKEV EKKLRCLLAD LPLPPELPGG DDLSKSPEEK KTTTQLHSKR RPKICGPRYG 180
  181 ET

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [691-1035]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEKDIDWGKL CVDKFDIIGI IGEGTYGQVY KARDKDTGEM VALKKVRLDN EKEGFPITAI  60
   61 REIKILRQLT HQSIINMKEI VTDKEDALDF KKDKGAFYLV FEYMDHDLMG LLESGLVHFN 120
  121 ENHIKSFMRQ LMEGLDYCHK KNFLHRDIKC SNILLNNRGQ IKLADFGLAR LYSSEESRPY 180
  181 TNKVITLWYR PPELLLGEER YTPAIDVWSC GCILGELFTK KPIFQANQEL AQLELISRIC 240
  241 GSPCPAVWPD VIKLPYFNTM KPKKQYRRKL REEFVFIPAA ALDLFDYMLA LDPSKRCTAE 300
  301 QALQCEFLRD VEPSKMPPPD LPLWQDCHEL WSKKRRRQKQ MGMTD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.045757
Match: 1vywA
Description: Structure of CDK2/Cyclin A with PNU-292137
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1036-1239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVSTIKAPRK DLSLGLDDSR TNTPQGVLPS SQLKSQGSSN VAPVKTGPGQ HLNHSELAIL  60
   61 LNLLQSKTSV NMADFVQVLN IKVNSETQQQ LNKINLPAGI LATGEKQTDP STPQQESSKP 120
  121 LGGIQPSSQT IQPKMETDAA QAAVQSAFAV LLTQLIKAQQ SKQKDVLLEE RENGSGHEAS 180
  181 LQLRPPPEPS TPVSGQDDLI QHQD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1240-1381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRILELTPEP DRPRILPPDQ RPPEPPEPPP VTEEDLDYRT ENQHVPTTSS SLTDPHAGVK  60
   61 AALLQLLAQH QPQDDPKREG GIDYQAGDTY VSTSDYKDNF GSSSFSSAPY VSNDGLGSSS 120
  121 APPLERRSFI GNSDIQSLDN YS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1382-1512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TASSHSGGPP QPSAFSESFP SSVAGYGDIY LNAGPMLFSG DKDHRFEYSH GPIAVLANSS  60
   61 DPSTGPESTH PLPAKMHNYN YGGNLQENPS GPSLMHGQTW TSPAQGPGYS QGYRGHISTS 120
  121 TGRGRGRGLP Y

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle