YRC Public Data Repository - Protein Structure Prediction

Protein:	OCH1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	396 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCH1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|49650982, gi\|... - gi\|49650982\|emb\|CAG77919.1\| YALI0F07260p [Yarrowia lipolytica], gi\|38488500\|emb\|CAD91643.1\| alpha 1,... gi\|49650982, gi\|... - gi\|50555407\|ref\|XP_505112.1\| YALI0F07260p [Yarrowia lipolytica], gi\|49650982\|emb\|CAG77919.1\| YALI0F0...	374.0	[0..7]	[396..8]
gi\|11289143 - gi\|11289143\|pir\|\|T50453 probable glycosyltransferase [imported] - fission yeast (Schizosaccharomyce...	373.0	[0..31]	[396..1]
HOC1_YEAST - Putative glycosyltransferase HOC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOC1 P... gi\|190409549 - gi\|190409549\|gb\|EDV12814.1\| mannosyltransferase [Saccharomyces cerevisiae RM11-1a] HOC1 - Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localize...	335.0	[0..3]	[395..13]
gi\|44985028 - gi\|44985028\|gb\|AAS53806.1\| AFR435Wp [Ashbya gossypii ATCC 10895] gi\|44985028, gi\|... - gi\|45198953\|ref\|NP_985982.1\| AFR435Wp [Ashbya gossypii ATCC 10895], gi\|44985028\|gb\|AAS53806.1\| AFR43...	323.0	[0..3]	[395..13]
gi\|85074763 - gi\|85074763\|ref\|XP_965749.1\| hypothetical protein NCU00609 [Neurospora crassa OR74A] gi\|28927562, gi\|... - gi\|32408617\|ref\|XP_324789.1\| hypothetical protein [Neurospora crassa], gi\|28927562\|gb\|EAA36513.1\| hy...	304.0	[0..98]	[396..55]
gi\|46135819, gi\|... - gi\|46135819\|ref\|XP_389601.1\| hypothetical protein FG09425.1 [Gibberella zeae PH-1], gi\|42554574\|gb\|E...	304.0	[0..86]	[396..44]
gi\|17978673 - gi\|17978673\|gb\|AAL49987.1\| putative mannosyltransferase [Candida albicans]	301.0	[0..83]	[396..46]
OCH1_CANAL - Initiation-specific alpha-1,6-mannosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876... gi\|238881006 - gi\|238881006\|gb\|EEQ44644.1\| hypothetical protein CAWG_02918 [Candida albicans WO-1] orf19.7391 - OCH1 CGDID:CAL0004830 Assembly 19, Contig19-2513 (118280, 117123) CDS, reverse complemented, transla...	300.0	[0..83]	[396..46]
gi\|33331887 - gi\|33331887\|gb\|AAQ11191.1\| putative mannosyltransferase [Pichia angusta]	296.0	[0..57]	[388..45]

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Predicted Domain #1

Region A:
Residues: [1-396]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLRLRSIV IGAAIAGSIL LLFNHGSIEG MEDLTEISML EDYTPEAANK DYVGQQEEEE  60
   61 LLYDQPSYIE EEEDPDLEAY LSDLEREELE HSLEELDEEN NYKLHLRYSF SQLQDFDEEN 120
  121 EAVHMIVPKD TYEFEVPYHA DIPKLIWQTS KDPFDREVMK YTRFWRINHP SYSHAVLDDE 180
  181 QSKALVISSF GDSSVSKISQ AYAMMPLPVL KADFFRYLVL LAKGGIYSDI DTAPLKHINN 240
  241 WIPREYRKRN IRLIVGIEAD PDRPDWNDYY ARRVQFCQWT IAAAPGHPIL WELVRRITDE 300
  301 TWKLHDSKKL SKNGESVMEW TGPGIWTDAI MDYLNWQYGP FSVENITNLE EPYLVGDVLI 360
  361 LPITAFSPGV GHMGSKSPND PMAYVQHFFA GSWKDD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.64
Match:	2bvlA
Description:	Crystal structure of the catalytic domain of toxin B from Clostridium difficile in complex with UDP, Glc and manganese ion
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-glycosyltransferase activity	6.01354989568484	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	5.66606808201136	bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity	5.62955108548526	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	5.60505224219681	bayes_pls_golite062009
mannosyltransferase activity	5.1732667004955	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	4.21261757812439	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	4.02812104984198	bayes_pls_golite062009
transferase activity	3.03489639421954	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.2967992874857	bayes_pls_golite062009
catalytic activity	1.73979371332125	bayes_pls_golite062009
nucleotidyltransferase activity	1.47767908405723	bayes_pls_golite062009
N-acetyllactosamine synthase activity	0.925872529464618	bayes_pls_golite062009
lactose synthase activity	0.925872529464618	bayes_pls_golite062009
uridylyltransferase activity	0.790072592167014	bayes_pls_golite062009
binding	0.594806047305175	bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	0.386636074342689	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: