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View Structure Prediction Details

Protein: PNPO
Organism: Homo sapiens
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNPO.

Description E-value Query
Range
Subject
Range
PNPO_MOUSE - Pyridoxine-5'-phosphate oxidase OS=Mus musculus GN=Pnpo PE=1 SV=1
1.0E-99 [1..261] [1..261]
PNPO_RAT - Pyridoxine-5'-phosphate oxidase OS=Rattus norvegicus GN=Pnpo PE=1 SV=1
2.0E-98 [1..261] [1..261]
gi|62898045 - gi|62898045|dbj|BAD96962.1| pyridoxine 5'-phosphate oxidase variant [Homo sapiens]
1.0E-96 [1..261] [1..261]
gi|73966182 - gi|73966182|ref|XP_537661.2| PREDICTED: similar to Pyridoxine-5-phosphate oxidase (Pyridoxamine-phos...
5.0E-96 [1..261] [1..261]
gi|109114125 - gi|109114125|ref|XP_001084391.1| PREDICTED: pyridoxine 5'-phosphate oxidase isoform 3 [Macaca mulatt...
3.0E-95 [1..261] [1..261]
gi|34784069 - gi|34784069|gb|AAH57246.1| Pnpo protein [Danio rerio]
8.0E-94 [7..261] [13..267]
PNPO_BOVIN - Pyridoxine-5'-phosphate oxidase OS=Bos taurus GN=PNPO PE=2 SV=1
9.0E-93 [1..261] [1..261]

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Predicted Domain #1
Region A:
Residues: [1-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTCWLRGVTA TFGRPAEWPG YLSHLCGRSA AMDLGPMRKS YRGDREAFEE THLTSLDPVK  60
   61 QFAAWFEEAV QCPDIGEANA MCLATCTRDG KPSARMLLLK GFGKDGFRFF TNFESRKGKE 120
  121 LDSNPFASLV FYWEPLNRQV RVEGPVKKLP EEEAECYFHS RPKSSQIGAV VSHQSSVIPD 180
  181 REYLRKKNEE LEQLYQDQEV PKPKSWGGYV LYPQVMEFWQ GQTNRLHDRI VFRRGLPTGD 240
  241 SPLGPMTHRG EEDWLYERLA P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 99.0
Match: 1nrgA
Description: Pyridoxine 5'-phoshate oxidase (PNP oxidase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pyridoxamine-phosphate oxidase activity 3.81533880638523 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1.18444956617957 bayes_pls_golite062009
catalytic activity 0.660906721832294 bayes_pls_golite062009
oxidoreductase activity 0.0268904833845668 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle