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View Structure Prediction Details

Protein: RPN2
Organism: Homo sapiens
Length: 631 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN2.

Description E-value Query
Range
Subject
Range
gi|36049 - gi|36049|emb|CAA68393.1| unnamed protein product [Homo sapiens]
961.0 [0..1] [631..1]
RPN2_PONAB - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Pongo abelii GN=RPN2 PE=...
gi|55728178 - gi|55728178|emb|CAH90839.1| hypothetical protein [Pongo abelii]
950.0 [0..1] [631..1]
gi|73991908 - gi|73991908|ref|XP_865679.1| PREDICTED: similar to ribophorin II precursor isoform 3 [Canis familiar...
926.0 [0..1] [631..1]
RPN2_RAT - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Rattus norvegicus GN=Rpn...
924.0 [0..1] [631..1]
RPN2_BOVIN - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Bos taurus GN=RPN2 PE=2 ...
922.0 [0..1] [631..1]
RPN2_MOUSE - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Mus musculus GN=Rpn2 PE=...
gi|55715762 - gb|AAH86186.1| Unknown (protein for MGC:98648) [Xenopus laevis]
918.0 [0..1] [631..1]

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Predicted Domain #1
Region A:
Residues: [1-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPGSSTVF LLALTIIAST WALTPTHYLT KHDVERLKAS LDRPFTNLES AFYSIVGLSS  60
   61 LGAQVPDAKK ACTYIRSNLD PSNVDSLFYA AQASQALSGC EISISNETKD LLLAAVSEDS 120
  121 SVTQIYHAVA ALSGFGL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.855 a.118.8 TPR-like
View Download 0.634 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.634 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.632 a.4.5 "Winged helix" DNA-binding domain
View Download 0.602 a.118.1 ARM repeat
View Download 0.582 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.574 a.4.5 "Winged helix" DNA-binding domain
View Download 0.525 c.23.12 Formate/glycerate dehydrogenase catalytic domain-like
View Download 0.513 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #2
Region A:
Residues: [138-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLASQEALSA LTARLSKEET VLATVQALQT ASHLSQQADL RSIVEEIEDL VARLDELGGV  60
   61 YLQFEEGLET TALFVAATYK LMDHVGTEPS IKEDQVIQLM NAIFSKKNFE SLSEAFSVAS 120
  121 AAAVLSHNRY HVPVVVVPEG SASDTHEQAI LRLQVTNVLS QPLTQATVKL EHAKSVASRA 180
  181 TVLQKTSFTP VGDVFELNFM NVKFSSGYYD FLVEVEGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [356-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRYIANTVEL RVKISTEVGI TNVDLSTVDK DQSIAPKTTR VTYPAKAKGT FIADSHQNFA  60
   61 LFFQLVDVNT 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.866 b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.860 d.17.1 Cystatin/monellin
View Download 0.858 b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.820 d.50.1 dsRNA-binding domain-like
View Download 0.781 b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.778 b.4.1 HSP40/DnaJ peptide-binding domain
View Download 0.764 b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.759 d.15.7 Immunoglobulin-binding domains
View Download 0.722 d.15.7 Immunoglobulin-binding domains
View Download 0.712 d.50.1 dsRNA-binding domain-like
View Download 0.668 g.41.17 Description not found.
View Download 0.572 g.41.17 Description not found.
View Download 0.561 d.58.7 RNA-binding domain, RBD
View Download 0.524 d.58.7 RNA-binding domain, RBD
View Download 0.509 d.9.1 Interleukin 8-like chemokines

Predicted Domain #4
Region A:
Residues: [426-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAELTPHQTF VRLHNQKTGQ EVVFVAEPDN KNVYKFELDT SERKIEFDSA SGTYTLYLII  60
   61 GDATLKNPIL WNVADVVIKF PEEEAPSTVL S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.729 d.19.1 MHC antigen-recognition domain
View Download 0.721 d.354.1 Description not found.
View Download 0.699 d.224.1 SufE-like
View Download 0.680 d.129.6 Description not found.
View Download 0.669 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.537 d.93.1 SH2 domain
View Download 0.503 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.445 d.93.1 SH2 domain
View Download 0.436 d.45.1 ClpS-like
View Download 0.373 b.1.18 E set domains
View Download 0.342 d.214.1 Hypothetical protein MTH1880
View Download 0.317 c.30.1 PreATP-grasp domain
View Download 0.292 d.45.1 ClpS-like

Predicted Domain #5
Region A:
Residues: [517-631]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNLFTPKQEI QHLFREPEKR PPTVVSNTFT ALILSPLLLL FALWIRIGAN VSNFTFAPST  60
   61 IIFHLGHAAM LGLMYVYWTQ LNMFQTLKYL AILGSVTFLA GNRMLAQQAV KRTAH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle