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View Structure Prediction Details

Protein: GAN
Organism: Homo sapiens
Length: 597 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GAN.

Description E-value Query
Range
Subject
Range
gi|60360272 - gi|60360272|dbj|BAD90380.1| mKIAA4221 protein [Mus musculus]
2.0E-99 [2..575] [86..647]
gi|109074005 - gi|109074005|ref|XP_001090114.1| PREDICTED: kelch-like 5 isoform 5 [Macaca mulatta]
1.0E-98 [2..575] [5..566]
gi|62087220 - gi|62087220|dbj|BAD92057.1| kelch-like 5 isoform 2 variant [Homo sapiens]
2.0E-98 [1..575] [26..591]
gi|62660471, gi|... - gi|62660471|ref|XP_223418.2| PREDICTED: similar to Kelch-like protein 5 [Rattus norvegicus], gi|5522...
6.0E-98 [2..575] [145..706]
gi|114593704 - gi|114593704|ref|XP_517151.2| PREDICTED: kelch-like 5 [Pan troglodytes]
2.0E-97 [4..575] [280..839]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGSAVSDP QHAARLLRAL SSFREESRFC DAHLVLDGEE IPVQKNILAA ASPYIRTKLN  60
   61 YNPPKDDGST YKIELEGISV MVMREILDYI FSGQIRLNED TIQDVVQAAD LLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 2ppiA
Description: No description for 2ppiA was found.

Predicted Domain #2
Region A:
Residues: [114-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTDLKTLCCE FLEGCIAAEN CIGIRDFALH YCLHHVHYLA TEYLETHFRD VSSTEEFLEL  60
   61 SPQKLKEVIS LEKLNVGNER YVFEAVIRWI AHDTEIRKVH MKDVMSALWV SGLDSSYLRE 120
  121 QMLNEPLVRE IVKECSNIP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.29
Match: 2eqxA
Description: No description for 2eqxA was found.

Predicted Domain #3
Region A:
Residues: [253-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSQPQQGEAM LANFKPRGYS ECIVTVGGEE RVSRKPTAAM RCMCPLYDPN RQLWIELAPL  60
   61 SMPRINHGVL SAEGFLFVFG GQDENKQTLS SGEKYDPDAN TWTALPPMNE ARHNFGIVEI 120
  121 DGMLYILGGE DGEKELISME CYDIYSKTWT KQPDLTMVRK IGCYAAMKKK IYAMGGGSYG 180
  181 KLFESVECYD PRTQQWTAIC PLKERRFGAV ACGVAMELYV FGGVRSREDA QGSEMVTCKS 240
  241 EFYHDEFKRW IYLNDQNLCI PASSSFVYGA VPIGASIYVI GDLDTGTNYD YVREFKRSTG 300
  301 TWHHTKPLLP SDLRRTGCAA LRIANCKLFR LQLQQGLFRI RVHSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.69897
Match: 1zgkA
Description: 1.35 angstrom structure of the Kelch domain of Keap1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle