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View Structure Prediction Details

Protein: PABPC1
Organism: Homo sapiens
Length: 636 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PABPC1.

Description E-value Query
Range
Subject
Range
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2
0.0 [1..636] [1..636]
gi|197097606 - gi|197097606|ref|NP_001126097.1| poly(A) binding protein, cytoplasmic 1 [Pongo abelii]
gi|55730342 - gi|55730342|emb|CAH91893.1| hypothetical protein [Pongo abelii]
0.0 [1..636] [1..636]
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1
0.0 [1..636] [1..636]
gi|73974164 - gi|73974164|ref|XP_857417.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
0.0 [1..636] [1..636]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPSAPSYPM ASLYVGDLHP DVTEAMLYEK FSPAGPILSI RVCRDMITRR SLGYAYVNFQ  60
   61 QPADAERALD TMNFDVIKGK PVRIMWSQRD PSLRKSGVGN IFIKNLDKSI DNKALYDTFS 120
  121 AFGNILSCKV VCDENGSKGY GFVHFETQEA AERAIEKMNG MLLNDRKVFV GRFKSRKERE 180
  181 AEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.69897
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.92126426323641 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [184-283]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GARAKEFTNV YIKNFGEDMD DERLKDLFGK FGPALSVKVM TDESGKSKGF GFVSFERHED  60
   61 AQKAVDEMNG KELNGKQIYV GRAQKKVERQ TELKRKFEQM 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.3
Match: 2do0A
Description: No description for 2do0A was found.

Predicted Domain #3
Region A:
Residues: [284-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQDRITRYQG VNLYVKNLDD GIDDERLRKE FSPFGTITSA KVMMEGGRSK GFGFVCFSSP  60
   61 EEATKAVTEM NGRIVATKPL YVALAQRKEE RQAHLTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 2d9pA
Description: No description for 2d9pA was found.

Predicted Domain #4
Region A:
Residues: [381-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYMQRMASVR AVPNPVINPY QPAPPSGYFM AAIPQTQNRA AYYPPSQIAQ LRPSPRWTAQ  60
   61 GARPHPFQNM PGAIRPAAPR PPFSTMRPAS SQVPRVMSTQ RVANTSTQTM GPRPAAAAAA 120
  121 ATPAVRTVPQ YKYAAGVRNP QQHLNAQPQV TMQQPAVHVQ GQEPLTASML ASAPPQEQKQ 180
  181 MLGERL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [567-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPLIQAMHPT LAGKITGMLL EIDNSELLHM LESPESLRSK VDEAVAVLQA HQAKEAAQKA  60
   61 VNSATGVPTV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.522879
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle