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View Structure Prediction Details

Protein: MATR3
Organism: Homo sapiens
Length: 847 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MATR3.

Description E-value Query
Range
Subject
Range
gi|114602033, gi... - gi|114602033|ref|XP_001172359.1| PREDICTED: matrin 3 isoform 12 [Pan troglodytes], gi|114602031|ref|...
0.0 [1..847] [1..847]
gi|40788339 - gi|40788339|dbj|BAA34443.2| KIAA0723 protein [Homo sapiens]
0.0 [1..847] [7..853]
gi|34878612, gi|... - gi|62664153|ref|XP_579423.1| PREDICTED: hypothetical protein XP_579423 [Rattus norvegicus], gi|61889...
0.0 [1..847] [1..845]
gi|109078824, gi... - gi|109078826|ref|XP_001114358.1| PREDICTED: matrin 3 isoform 7 [Macaca mulatta], gi|109078824|ref|XP...
0.0 [1..847] [1..847]
gi|197101369 - gi|197101369|ref|NP_001126563.1| matrin 3 isoform 1 [Pongo abelii]
gi|55731929 - gi|55731929|emb|CAH92673.1| hypothetical protein [Pongo abelii]
0.0 [1..847] [1..847]
MATR3_MOUSE - Matrin-3 OS=Mus musculus GN=Matr3 PE=1 SV=1
0.0 [1..847] [1..846]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSFQQSSL SRDSQGHGRD LSAAGIGLLA AATQSLSMPA SLGRMNQGTA RLASLMNLGM  60
   61 SSSLNQQGAH SALSSASTSS HNLQSIFNIG SRGPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSSQHRGDA DQASNILASF GLSARDLDEL SRYPEDKITP ENLPQILLQL KRRRTEEGPT  60
   61 LSYGRDGRSA TR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [168-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPPYRVPRDD WEEKRHFRRD SFDDRGPSLN PVLDYDHGSR SQESGYYDRM DYEDDRLRDG  60
   61 ERCRDDSFFG ETSHNYHKFD SEYERMGRGP GPLQERSLFE KKRGAPPSSN IEDFHGLLPK 120
  121 GYPHLCSICD LPVHSNKEWS QHINGASHSR RCQLLLEIYP EWNPDNDTGH TMGDPFMLQQ 180
  181 STNPAPGILG PPPPSFHLGG PAVGPRGN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [376-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGAGNGNLQG PRHMQKGRVE TSRVVHIMDF QRGKNLRYQL LQLVEPFGVI SNHLILNKIN  60
   61 EAFIEMATTE DAQAAVDYYT TTPALVFGKP VRVHLSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1x4fA
Description: Solution structure of the second RRM domain in Matrin 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.26550630643712 bayes_pls_golite062009
nucleic acid binding 2.02897811404491 bayes_pls_golite062009
RNA binding 1.45577328897026 bayes_pls_golite062009
mRNA binding 0.274978159646657 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [473-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYKRIKKPEG KPDQKFDQKQ ELGRVIHLSN LPHSGYSDSA VLKLAEPYGK IKNYILMRMK  60
   61 SQAFIEMETR EDAMAMVDHC LKKALWFQGR CVKVDLSEKY KKLVLRIPNR GIDLLKKDKS 120
  121 RKRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.23
Match: 1x4fA
Description: Solution structure of the second RRM domain in Matrin 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.10183662096756 bayes_pls_golite062009
nucleic acid binding 1.76030419422519 bayes_pls_golite062009
RNA binding 1.04699342909932 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [597-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSPDGKESPS DKKSKTDGSQ KTESSTEGKE QEEKSGEDGE KDTKDDQTEQ EPNMLLESED  60
   61 ELLVD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [662-847]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEAAALLES GSSVGDETDL ANLGDVASDG KKEPSDKAVK KDGSASAAAK KKLKKVDKIE  60
   61 ELDQENEAAL ENGIKNEENT EPGAESSENA DDPNKDTSEN ADGQSDENKD DYTIPDEYRI 120
  121 GPYQPNVPVG IDYVIPKTGF YCKLCSLFYT NEEVAKNTHC SSLPHYQKLK KFLNKLAEER 180
  181 RQKKET

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle