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View Structure Prediction Details

Protein: UPF3A
Organism: Homo sapiens
Length: 476 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UPF3A.

Description E-value Query
Range
Subject
Range
gi|7549210 - gi|7549210|gb|AAF63787.1|AF142406_1 200 kDa antigen p200 [Babesia bigemina]
1.0E-43 [2..476] [221..693]
gi|24020878, gi|... - gi|50979202|ref|NP_001003352.1| neurofilament, heavy polypeptide 200kDa [Canis lupus familiaris], gi...
4.0E-42 [2..476] [513..988]
gi|8163668 - gi|8163668|gb|AAF73792.1|AF154023_1 surface protein PspC [Streptococcus pneumoniae]
3.0E-41 [25..475] [39..516]
unc-89 - status:Partially_confirmed UniProt:O01761 protein_id:AAP68958.1
3.0E-38 [23..476] [1352..1812]
gi|62360137, gi|... - gi|70801193|gb|AAZ11101.1| hypothetical protein, conserved [Trypanosoma brucei], gi|62360137|gb|AAX8...
gi|71753647, gi|... - gi|72388472|ref|XP_844660.1| hypothetical protein [Trypanosoma brucei TREU927], gi|71753647|ref|XP_8...
6.0E-38 [2..475] [449..926]
gi|205686 - gi|205686|gb|AAA41695.1| heavy neurofilament subunit
8.0E-38 [7..475] [231..699]

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Predicted Domain #1
Region A:
Residues: [1-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSEKEGAGG LRAAVAARGP SGREKLSALE VQFHRDSQQQ EAETPPTSSS GCGGGAGKPR  60
   61 EEKRTALSKV VIRRLPPGLT KEQLEEQLRP LPAHDYFEFF AADLSLYPHL YSRAYINFRN 120
  121 PDDILLFRDR FDGYIFLDSK GLEYPAVVEF APFQKIAKKK LRKKDAKTGS IEDDPEYKKF 180
  181 LETYCVEEEK TSANPETLLG EMEAKTRELI ARRTTPLLEY IKNRKLEKQR IREEKREERR 240
  241 RRELEKKRLR EEEKRRRREE ERCKKKETDK QKKIAEKEVR IKLLKKPEKG EEPTTEKPKE 300
  301 RGEEIDTGGG KQESCAPGAV VKARPMEGSL EEPQETSHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.221849
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [340-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSDKEHRDVE RSQEQESEAQ RYHVDDGRRH RAHHEPERLS RRSEDEQRWG KGPGQDRGKK  60
   61 GSQDSGAPGE AMERLGRAQR CDDSPAPRKE RLANKDRPAL QLYDPGARFR ARECGGNRRI 120
  121 CKAEGSGTGP EKREEAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.39794
Match: 1w9rA
Description: Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle