YRC Public Data Repository - Protein Structure Prediction

Protein:	CUTC
Organism:	Homo sapiens
Length:	273 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CUTC.

Description	E-value	Query Range	Subject Range
gi\|62901834 - gi\|62901834\|gb\|AAY18868.1\| CGI-32 [synthetic construct]	0.0	[2..273]	[13..284]
gi\|109090222 - gi\|109090222\|ref\|XP_001106529.1\| PREDICTED: cutC copper transporter homolog [Macaca mulatta]	0.0	[1..273]	[1..273]
gi\|7705728, gi\|4... - gi\|7705728\|ref\|NP_057044.1\| cutC copper transporter homolog [Homo sapiens], gi\|4680703\|gb\|AAD27741.1...	0.0	[1..273]	[1..273]
gi\|109463988, gi... - gi\|62642320\|ref\|XP_342053.2\| PREDICTED: similar to Copper homeostasis protein cutC homolog [Rattus n...	0.0	[3..273]	[2..272]
CUTC_MOUSE - Copper homeostasis protein cutC homolog OS=Mus musculus GN=Cutc PE=1 SV=1	0.0	[3..273]	[2..272]
gi\|73998621 - gi\|73998621\|ref\|XP_534987.2\| PREDICTED: similar to Copper homeostasis protein cutC homolog [Canis fa...	0.0	[1..273]	[1..273]
gi\|56556528, gi\|... - gi\|58332136\|ref\|NP_001011220.1\| hypothetical protein LOC496655 [Xenopus (Silurana) tropicalis], gi\|5...	0.0	[22..272]	[2..252]
gi\|80477695, gi\|... - gi\|80477695\|gb\|AAI08642.1\| MGC131328 protein [Xenopus laevis], gi\|148238237\|ref\|NP_001090148.1\| hypo...	0.0	[22..272]	[2..252]
gi\|53131730, gi\|... - gi\|57529838\|ref\|NP_001006503.1\| cutC copper transporter homolog [Gallus gallus], gi\|53131730\|emb\|CAG...	0.0	[25..272]	[4..251]

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Predicted Domain #1

Region A:
Residues: [1-273]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRQGASSER KRARIPSGKA GAANGFLMEV CVDSVESAVN AERGGADRIE LCSGLSEGGT  60
   61 TPSMGVLQVV KQSVQIPVFV MIRPRGGDFL YSDREIEVMK ADIRLAKLYG ADGLVFGALT 120
  121 EDGHIDKELC MSLMAICRPL PVTFHRAFDM VHDPMAALET LLTLGFERVL TSGCDSSALE 180
  181 GLPLIKRLIE QAKGRIVVMP GGGITDRNLQ RILEGSGATE FHCSARSTRD SGMKFRNSSV 240
  241 AMGASLSCSE YSLKVTDVTK VRTLNAIAKN ILV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	90.522879
Match:	1twdA
Description:	Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
copper ion binding	2.32959091323982	bayes_pls_golite062009
binding	1.75231237460254	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: