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View Structure Prediction Details

Protein: SGPP1
Organism: Homo sapiens
Length: 441 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SGPP1.

Description E-value Query
Range
Subject
Range
gi|55640905 - gi|55640905|ref|XP_522876.1| PREDICTED: sphingosine-1-phosphatase [Pan troglodytes]
0.0 [1..441] [1..441]
gi|13447199 - gi|13447199|gb|AAK26660.1|AF349315_1 sphingosine-1-phosphate phosphatase [Homo sapiens]
0.0 [1..441] [1..441]
gi|73964194 - gi|73964194|ref|XP_547850.2| PREDICTED: similar to sphingosine-1-phosphatase [Canis familiaris]
0.0 [1..441] [1..445]
gi|109479537 - gi|109479537|ref|XP_001080791.1| PREDICTED: similar to Sphingosine-1-phosphate phosphatase 1 (Sphing...
0.0 [1..441] [101..530]
SGPP1_MOUSE - Sphingosine-1-phosphate phosphatase 1 OS=Mus musculus GN=Sgpp1 PE=1 SV=1
3.0E-97 [1..441] [1..430]
gi|76677311, gi|... - gi|76677311|ref|XP_595039.2| PREDICTED: similar to sphingosine-1-phosphatase [Bos taurus], gi|118150...
7.0E-88 [1..441] [1..445]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLRQRLAQL VGRLQDPQKV ARFQRLCGVE APPRRSADRR EDEKAEAPLA GDPRLRGRQP  60
   61 GAPGGPQPPG SD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNQCPAKPDG GGAPNGVRNG LAAELGPASP RRAGALRRNS LTGEEGQLAR VSNWPLYCLF  60
   61 CFGTELGNEL FYILFFPFWI WNLDPLVGRR LVVIWVLVMY LGQCTKDIIR WPRPASPPVV 120
  121 KLEVFYNSEY SMPSTHAMSG TAIPISMVLL TYGRWQYPLI YGLILIPCWC SLVCLSRIYM 180
  181 GMHSILDIIA GFLYTILILA VFYPFVDLID NFNQTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.221849
Match: 1d2tA
Description: Bacterial acid phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.767627914425245 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [289-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYAPFIIIGL HLALGIFSFT LDTWSTSRGD TAEILGSGAG IACGSHVTYN MGLVLDPSLD  60
   61 TLPLAGPPIT VTLF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [363-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKAILRILIG MVFVLIIRDV MKKITIPLAC KIFNIPCDDI RKARQHMEVE LPYRYITYGM  60
   61 VGFSITFFVP YIFFFIGIS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle