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View Structure Prediction Details

Protein: ZMYND11
Organism: Homo sapiens
Length: 562 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZMYND11.

Description E-value Query
Range
Subject
Range
gi|114629049 - gi|114629049|ref|XP_001135863.1| PREDICTED: zinc finger, MYND domain containing 11 isoform 5 [Pan tr...
0.0 [1..562] [24..585]
gi|109088000 - gi|109088000|ref|XP_001100057.1| PREDICTED: zinc finger, MYND domain containing 11 isoform 5 [Macaca...
0.0 [1..562] [41..602]
gi|197099320 - gi|197099320|ref|NP_001126420.1| zinc finger, MYND domain containing 11 [Pongo abelii]
gi|55731392 - gi|55731392|emb|CAH92410.1| hypothetical protein [Pongo abelii]
0.0 [1..562] [41..602]
gi|73949130, gi|... - gi|73949132|ref|XP_858784.1| PREDICTED: similar to Zinc finger MYND domain containing protein 11 (Ad...
0.0 [1..562] [41..602]
gi|71059987 - gi|71059987|emb|CAJ18537.1| Zmynd11 [Mus musculus]
0.0 [1..562] [1..562]
gi|42734403, gi|... - gi|42734403|ref|NP_976242.1| zinc finger, MYND domain containing 11 alpha isoform [Rattus norvegicus...
0.0 [1..562] [1..562]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRVHGMHPK ETTRQLSLAV KDGLIVETLT VGCKGSKAGI EQEGYWLPGD EIDWETENHD  60
   61 WYCFECHLPG EVLICDLC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.240 0.280 negative regulation of transcription from RNA polymerase II promoter a.4.5 "Winged helix" DNA-binding domain
View Download 0.274 0.215 negative regulation of transcription from RNA polymerase II promoter a.3.1 Cytochrome c
View Download 0.349 0.134 negative regulation of transcription from RNA polymerase II promoter d.15.4 2Fe-2S ferredoxin-like

Predicted Domain #2
Region A:
Residues: [79-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FRVYHSKCLS DEFRLRDSSS PWQCPVCRSI KKKNTNKQEM GTYLRFIVSR MKERAIDLNK  60
   61 KGKDNKHPMY RRLVHSAVDV PTIQEKVNEG KYRSYEEFKA DAQLLLHNTV IFYGADSEQA 120
  121 DIARMLYKDT CHELDELQLC KNCFYLSNAR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.30103
Match: 2f6jA
Description: No description for 2f6jA was found.

Predicted Domain #3
Region A:
Residues: [229-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDNWFCYPCI PNHELVWAKM KGFGFWPAKV MQKEDNQVDV RFFGHHHQRA WIPSENIQDI  60
   61 TVNIHRLHVK RSMGWKKACD ELELHQRFLR EGRFWKSKNE DRGEEEAESS ISSTSNEQLK 120
  121 VTQEPRAKKG RRNQSVEPKK EEPEPETEAV SSSQEIPTMP QPIEKVSVST QTKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 2b8aA
Description: High Resolution Structure of the HDGF PWWP Domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [403-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSASSPRMLH RSTQTTNDGV CQSMCHDKYT KIFNDFKDRM KSDHKRETER VVREALEKLR  60
   61 SEMEEEKRQA VN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.786 a.4.1 Homeodomain-like
View Download 0.601 a.4.5 "Winged helix" DNA-binding domain
View Download 0.777 a.4.1 Homeodomain-like
View Download 0.668 a.4.1 Homeodomain-like
View Download 0.634 a.4.1 Homeodomain-like

Predicted Domain #5
Region A:
Residues: [475-562]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAVANMQGEM DRKCKQVKEK CKEEFVEEIK KLATQHKQLI SQTKKKQWCY NCEEEAMYHC  60
   61 CWNTSYCSIK CQQEHWHAEH KRTCRRKR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.31
Match: 2d8qA
Description: No description for 2d8qA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle