YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30582353, gi\|...
Organism:	Homo sapiens
Length:	449 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30582353, gi|....

Description	E-value	Query Range	Subject Range
gi\|49092446, gi\|... - gi\|67526179\|ref\|XP_661151.1\| hypothetical protein AN3547.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	2.0E-60	[14..447]	[765..1206]
gi\|116195872, gi... - gi\|88180447\|gb\|EAQ87915.1\| hypothetical protein CHGG_04534 [Chaetomium globosum CBS 148.51], gi\|1161...	2.0E-60	[19..447]	[801..1237]
gi\|113476999, gi... - gi\|113476999\|ref\|YP_723060.1\| peptidase-like [Trichodesmium erythraeum IMS101], gi\|110168047\|gb\|ABG5...	7.0E-60	[1..446]	[198..658]
gi\|115379453, gi... - gi\|115379453\|ref\|ZP_01466552.1\| tetratricopeptide repeat family [Stigmatella aurantiaca DW4/3-1], gi...	1.0E-58	[20..445]	[324..757]
gi\|159894698, gi... - gi\|159901659\|ref\|YP_001547905.1\| TPR repeat-containing protein [Herpetosiphon aurantiacus ATCC 23779...	3.0E-57	[2..446]	[621..1073]
gi\|115443450, gi... - gi\|115443450\|ref\|XP_001218532.1\| predicted protein [Aspergillus terreus NIH2624], gi\|114188401\|gb\|EA...	2.0E-54	[11..432]	[839..1268]
gi\|25531557 - pir\|\|AD2154 hypothetical protein all2787 [imported] - Nostoc sp. (strain PCC 7120) gi\|17230279, gi\|... - gi\|17230279\|ref\|NP_486827.1\| hypothetical protein all2787 [Nostoc sp. PCC 7120], gi\|17131880\|dbj\|BAB...	3.0E-53	[38..441]	[451..861]

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Predicted Domain #1

Region A:
Residues: [1-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMESTATAA VAAELVSADK IEDVPAPSTS ADKVESLDVD SEAKKLLGLG QKHLVMGDIP  60
   61 AAVNAFQEAA SLLGKKYGET ANECGEAFFF YGKSLLELAR MENGVLGNAL EGVHVEEEEG 120
  121 EKTEDESLVE NNDNIDETEG SEEDDKENDK TEEMPNDSVL ENKSLQENEE EEIGNLELAW 180
  181 DMLDLAKIIF KRQETKEAQL YAAQAHLKLG EVSVESENYV QAVEEFQSCL NLQEQYLEAH 240
  241 DRLLAETHYQ LGLAYGYNSQ YDEAVAQFSK SIEVIENRMA VLNEQVKEAE GSSAEYKKEI 300
  301 EELKELLPEI REKIEDAKES QRSGNVAELA LKATLVESST SGFTPGGGGS SVSMIASRKP 360
  361 TDGASSSNCV TDISHLVRKK RKPEEESPRK DDAKKAKQEP EVNGGSGDAV PSGNEVSENM 420
  421 EEEAENQAES RAAVEGTVEA GATVESTAC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.30103
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.02652482814057	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: