YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAST
Organism:	Homo sapiens
Length:	616 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAST.

Description	E-value	Query Range	Subject Range
gi\|3257095, gi\|1... - gi\|3257095\|dbj\|BAA29778.1\| 840aa long hypothetical cell division control protein (transitional endop... gi\|7435754 - pir\|\|H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...	1.0E-97	[17..609]	[196..821]
gi\|7435759, gi\|5... - pir\|\|F75154 cell division control protein 48, aaa family (cdc48-1) PAB2086 - Pyrococcus abyssi (stra... gi\|5457827, gi\|1... - gi\|5457827\|emb\|CAB49317.1\| Cdc48 cell division control protein 48, AAA family [Pyrococcus abyssi GE5...	1.0E-95	[27..613]	[176..792]
gi\|18894073, gi\|... - gi\|18978254\|ref\|NP_579611.1\| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi\|18894073...	3.0E-95	[24..613]	[174..793]
gi\|57159416, gi\|... - gi\|57641092\|ref\|YP_183570.1\| cell division protein CDC48 [Thermococcus kodakarensis KOD1], gi\|571594...	5.0E-95	[29..613]	[178..793]
Y1297_ARCFU - Cell division cycle protein 48 homolog AF_1297 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 ... Y1297_ARCFU, YC9... - (O28972) Cell division cycle protein 48 homolog AF1297, Cell division cycle protein 48 homolog AF_12...	2.0E-94	[16..611]	[165..728]
gi\|18159541, gi\|... - gi\|18312110\|ref\|NP_558777.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	3.0E-93	[26..610]	[172..713]

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Predicted Domain #1

Region A:
Residues: [1-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSPGGRGKK KGSGGASNPV PPRPPPPCLA PAPPAAGPAP PPESPHKRNL YYFSYPLFVG  60
   61 FALLRLVAFH LGLLFVWLCQ RFSRALMAAK RSSGAAPAPA SASAPAPV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [109-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGGEAERVRV FHKQAFEYIS IALRIDEDEK AGQKEQAVEW YKKGIEELEK GIAVIVTGQG  60
   61 EQCERARRLQ AKMMTNLVMA KDRLQLLEKM QPVLPFSKSQ TDVYNDSTNL AC

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.42
Match:	2dl1A
Description:	No description for 2dl1A was found.

Predicted Domain #3

Region A:
Residues: [221-320]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNGHLQSESG AVPKRKDPLT HTSNSLPRSK TVMKTGSAGL SGHHRAPSYS GLSMVSGVKQ  60
   61 GSGPAPTTHK GTPKTNRTNK PSTPTTATRK KKDLKNFRNV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [321-616]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSNLANLIMN EIVDNGTAVK FDDIAGQDLA KQALQEIVIL PSLRPELFTG LRAPARGLLL  60
   61 FGPPGNGKTM LAKAVAAESN ATFFNISAAS LTSKYVGEGE KLVRALFAVA RELQPSIIFI 120
  121 DEVDSLLCER REGEHDASRR LKTEFLIEFD GVQSAGDDRV LVMGATNRPQ ELDEAVLRRF 180
  181 IKRVYVSLPN EETRLLLLKN LLCKQGSPLT QKELAQLARM TDGYSGSDLT ALAKDAALGP 240
  241 IRELKPEQVK NMSASEMRNI RLSDFTESLK KIKRSVSPQT LEAYIRWNKD FGDTTV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.154902
Match:	2qp9X
Description:	No description for 2qp9X was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits